N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine(CAS: 171856-09-0)

This compound is a crystalline solid with a molecular weight of approximately 610.55 g/mol. It has limited water solubility and is highly reactive, particularly with bases. It is stable under normal conditions but should be protected from moisture. Reactivity is enhanced in basic conditions, making it suitable for peptide coupling reactions.

The compound is synthesized through a multi-step process involving fluorenylmethyloxycarbonyl (Fmoc) protection, followed by amidation and acylation reactions. Commonly, the Fmoc group is introduced using Fluorenylmethoxycarbonyl chloride (Fmoc-Cl), and the product is purified by column chromatography. This process requires careful control of pH and temperature to ensure high yield and selectivity.

This compound is primarily used in pharmaceuticals, where it serves as an intermediate in the synthesis of complex peptides and proteins. It is also utilized in polymer science for the modification of polymers and in semiconductor manufacturing for specific surface chemistry applications.

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate safety measures, and the Material Safety Data Sheet (MSDS) should be consulted for detailed handling instructions.