Compound Q&A
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine (CAS: 171856-09-0) typically synthesized?
Answer
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine](https://static.chemtradehub.com/structs/171/171856-09-0-90d6.webp "N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine")
The compound is synthesized through a multi-step process involving fluorenylmethyloxycarbonyl (Fmoc) protection, followed by amidation and acylation reactions. Commonly, the Fmoc group is introduced using Fluorenylmethoxycarbonyl chloride (Fmoc-Cl), and the product is purified by column chromatography. This process requires careful control of pH and temperature to ensure high yield and selectivity.
About
CAS No
171856-09-0
English Name
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine
Molecular Formula
C26H32N2O6
Molecular Weight
468.55 g/mol
SMILES
CC(C)(C)OC(=O)NCCCCN(CC(=O)O)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChIKey
MNAXPVXIHALBEF-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine — Shanghai Yinxin Laboratory Equipment Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdd97a57537e5c8069adfb/67cdd97a57537e5c8069adfb-logo.webp){kind=logo}
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}