4-Chloro-3-nitrobenzaldehyde

Basic Information

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CAS Number

16588-34-4

Molecular Formula

C7H4ClNO3

Molecular Weight

185.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

60.0 to 63.0 deg-C

Boiling Point

299.8 ℃ at 760 mmHg

Water Solubility

4 g/L (98 ºC)

Flash Point

135.1 °C

Solubility

4g/l

Refractive Index

1.6000 (estimate)

SMILES

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C1=CC(=C(C=C1C=O)[N+](=O)[O-])Cl

InChI

InChI=1S/C7H4ClNO3/c8-6-2-1-5(4-10)3-7(6)9(11)12/h1-4H

InChIKey

HETBKLHJEWXWBM-UHFFFAOYSA-N

LogP

2.58390

Complexity

192

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

4-Chloro 3-nitrobenzaldehyde
3-nitro-4-Chlorobenzaldehyde
NS00025430
Q27256769
Z104476600
AKOS000119596
SY018230
NSC-68097
16588-34-4
NSC 68097
EINECS 240-645-7
DTXCID0024846
SCHEMBL560001
AM84217
4-Chloro-3-nitrobenzaldehyde, 98%
FT-0618080
BDBM50101956
HETBKLHJEWXWBM-UHFFFAOYSA-
STR00866
NCGC00256296-01
J-010233
2-chloro-5-formylnitrobenzene
A810679
3nitro-4-chlorobenzaldehyde
PS-5295
UNII-389H8733F1
389H8733F1
CS-W016936
4-Chloro-3-nitrobenzaldehyde
NSC68097
CAS-16588-34-4

MDL Number

MFCD00007078

Customs Code

2913000090

FAQ

What are the physical and chemical properties of 4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4)?

4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4) is a crystalline solid with a molecular weight of approximately 202.01 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, particularly towards nucleophiles due to the presence of the nitro and chloro groups. It is used as a precursor in various organic synthesis reactions.

How is 4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4) typically synthesized?

4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4) can be synthesized by the nitration of 4-chlorobenzaldehyde, followed by the reduction of the nitro group to an aldehyde using a suitable reducing agent such as sodium borohydride or catalytic hydrogenation. The reaction is typically carried out under mild conditions to achieve high yield and selectivity.

What industries use 4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4)?

4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of medicinal compounds. It also finds applications in the polymer industry for the preparation of functional polymers and in the semiconductor industry for the development of new materials and devices.

What precautions should be taken when handling 4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4)?

When handling 4-Chloro-3-nitrobenzaldehyde (CAS: 16588-34-4), it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area, preferably a fume hood. In case of spillage, immediately clean up with appropriate absorbent material and follow the safety data sheet (SDS) guidelines for disposal. Always consult the SDS for specific safety information.