5-bromo-3-nitro-pyridin-2-ol

Basic Information

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CAS Number

15862-34-7

Molecular Formula

C5H3BrN2O3

Molecular Weight

218.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

247°C

Boiling Point

296.7℃ at 760 mmHg

Density

1.98

Flash Point

133.2 °C

Refractive Index

1.647

SMILES

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C1=C(C(=O)NC=C1Br)[N+](=O)[O-]

InChI

InChI=1S/C5H3BrN2O3/c6-3-1-4(8(10)11)5(9)7-2-3/h1-2H,(H,7,9)

InChIKey

WXRLCVUDLFFTFF-UHFFFAOYSA-N

LogP

1.98110

Complexity

276

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

EN300-52723
BP-10198
2-HYDROXY-3-NITRO-5-BROMOPYRIDINE
BCP23135
AKOS000266530
CCG-202957
UNII-LAS8HHD2PX
LAS8HHD2PX
CS-W002138
SY019774
NSC170563
HY-W002138
5-bromo-3-nitro-2-hydroxypyridine
GS-6739
AM20050845
EINECS 239-989-0
5-Bromo-3-nitro-2-pyridinol
WXRLCVUDLFFTFF-UHFFFAOYSA-N
FT-0600935
5-Bromo-2-hydroxy-3-nitropyridine
NSC-170563
SCHEMBL13617483
SCHEMBL173688
12X-0947
3-nitro-5-bromo-2-pyridone
3-Bromo-6-hydroxy-5-nitropyridine
5-bromo-2-hydroxy-3-nitro-pyridine
5-Bromo-3-nitro-2(1H)-pyridinone
15862-34-7
5-bromo-3-nitropyridin-2(1H)-one
DTXSID30166481

MDL Number

MFCD00023473

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7)?

5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7) is a crystalline solid with a molecular weight of approximately 221.04 g/mol. It has a high solubility in aqueous solutions and is known for its reactivity, particularly with reducing agents and nucleophiles. It can undergo substitution and nitration reactions with high selectivity and good yields.

How is 5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7) typically synthesized?

5-bromo-3-nitro-pyridin-2-ol is commonly synthesized via the nitration of 5-bromo-pyridin-2-ol followed by bromination. The nitration step uses nitric acid and sulfuric acid as the oxidizing agent, while the bromination uses bromine in carbon tetrachloride or another inert solvent. The process typically yields a high purity product with good selectivity.

What industries use 5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7)?

5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7) is used in various industries including pharmaceuticals, where it serves as a precursor for drug synthesis, and in chemical research for its reactivity in organic synthesis. It is also utilized in polymer chemistry and as a reagent in analytical and sensor applications.

What precautions should be taken when handling 5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7)?

When handling 5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7), it is essential to wear proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risk. Dispose of any spills immediately according to the Material Safety Data Sheet (MSDS) guidelines. Ensure that all chemicals are stored in a cool, dry place away from direct sunlight and ignition sources.