5-bromo-3-nitro-pyridin-2-ol(CAS: 15862-34-7)

5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7) is a crystalline solid with a molecular weight of approximately 221.04 g/mol. It has a high solubility in aqueous solutions and is known for its reactivity, particularly with reducing agents and nucleophiles. It can undergo substitution and nitration reactions with high selectivity and good yields.

5-bromo-3-nitro-pyridin-2-ol is commonly synthesized via the nitration of 5-bromo-pyridin-2-ol followed by bromination. The nitration step uses nitric acid and sulfuric acid as the oxidizing agent, while the bromination uses bromine in carbon tetrachloride or another inert solvent. The process typically yields a high purity product with good selectivity.

5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7) is used in various industries including pharmaceuticals, where it serves as a precursor for drug synthesis, and in chemical research for its reactivity in organic synthesis. It is also utilized in polymer chemistry and as a reagent in analytical and sensor applications.

When handling 5-bromo-3-nitro-pyridin-2-ol (CAS: 15862-34-7), it is essential to wear proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risk. Dispose of any spills immediately according to the Material Safety Data Sheet (MSDS) guidelines. Ensure that all chemicals are stored in a cool, dry place away from direct sunlight and ignition sources.