Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate | CAS No. 158257-41-1
Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate
Basic Information
CAS Number
158257-41-1
Molecular Formula
C14H15NO5
Molecular Weight
277.28 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
368°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- AS-3214
- Z-VAL-NCA
- 3-Oxazolidinecarboxylic acid, 4-(1-methylethyl)-2,5-dioxo-, phenylmethyl ester, (4S)-
- (S)-Benzyl 4-isopropyl-2,5-dioxooxazolidine-3-carboxylate
- benzyl (4S)-2,5-dioxo-4-(propan-2-yl)-1,3-oxazolidine-3-carboxylate
- AKOS015911917
- CS-M3184
- MFCD00274015
- J-009486
- (S)-4-(1-Methylethyl)-2,5-dioxo-3-oxazolidinecarboxylic Acid Phenylmethyl Ester;N-Cbz-L-valine N-Carboxyanhydride
- SCHEMBL5166676
- 158257-41-1
- (S)-3-(Benzyloxycarbonyl)-4-isopropyl-2,5-oxazolidinedione
- Benzyl (4S)-2,5-dioxo-4-propan-2-yl-1,3-oxazolidine-3-carboxylate
- AC-31074
- ZB1796
- DTXSID30453989
- (S)-Benzyl4-isopropyl-2,5-dioxooxazolidine-3-carboxylate
- Z-L-Valine NCA
- 3-Oxazolidinecarboxylicacid, 4-(1-methylethyl)-2,5-dioxo-, phenylmethyl ester, (4S)-
- Benzyl (4S)-2,5-dioxo-4-(propan-2-yl)-1,3-oxazolidine-3-carboxylate
- benzyl (4S)-2,5-dioxo-4-propan-2-yl-1,3-oxazolidine-3-carboxylate
- N-Cbz-L-valine N-Carboxyanhydride
- Valine NCA
- CBZ-Val-NCA
- Z-Valine, NCA
- CBZ-L-valine acid NCA
- Z-L-Valin carboxyanhydride
- Z-VAINE NCA[FOR VALGANCICLOVIR]
- (S)-3-(BENZYLOXYCARBONYL)-4-ISOPROPYL
- benzyl(S)-4-isopropyl-2,5-dioxooxazolidine-3-carboxylate
MDL Number
MFCD00274015
Customs Code
2934999090
FAQ
What are the physical and chemical properties of Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate (CAS: 158257-41-1)?
Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate is a white crystalline solid with a molecular weight of approximately 276.36 g/mol. It has a low solubility in water (less than 0.1 g/100 mL at 20°C) but is more soluble in organic solvents. The compound is highly reactive due to the presence of the oxazolidine ring and the carboxylic acid moiety. It is also prone to hydrolysis and esterification reactions.
How is Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate (CAS: 158257-41-1) typically synthesized?
Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate can be synthesized using a multistep process involving the introduction of the isopropyl group and the oxazolidine skeleton. Common synthesis methods include condensation reactions and ring closing metathesis (RCM) followed by selective oxidation. The reaction is typically carried out under anhydrous conditions using appropriate solvents and catalysts to ensure high yield and selectivity.
What industries use Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate (CAS: 158257-41-1)?
Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate finds applications in various industries, particularly in pharmaceuticals for the synthesis of active pharmaceutical ingredients (APIs) and intermediates. It is also used in the polymer industry as a monomer for the production of functional polymers. Additionally, it has potential applications in the sensor industry for developing gas-sensing materials and in the semiconductor industry for specific chemical processes.
What precautions should be taken when handling Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate (CAS: 158257-41-1)?
When handling Benzyl (4S)-4-isopropyl-2,5-dioxo-1,3-oxazolidine-3-carboxylate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed down. Always consult the Safety Data Sheet (SDS) for specific handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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