Cecropin A (1-7)-Melittin A (2-9) amide

Basic Information

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CAS Number

157606-25-2

Molecular Formula

C89H152N22O15

Molecular Weight

1770.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCCN)N

InChI

InChI=1S/C89H152N22O15/c1-14-56(12)75(87(124)98-50-72(112)99-57(13)77(114)109-73(54(8)9)89(126)108-69(46-53(6)7)83(120)103-65(37-23-28-42-93)81(118)110-74(55(10)11)88(125)104-67(76(96)113)44-51(2)3)111-82(119)66(38-24-29-43-94)100-79(116)63(35-21-26-40-91)101-85(122)70(47-58-30-16-15-17-31-58)107-84(121)68(45-52(4)5)106-80(117)64(36-22-27-41-92)102-86(123)71(105-78(115)61(95)33-20-25-39-90)48-59-49-97-62-34-19-18-32-60(59)62/h15-19,30-32,34,49,51-57,61,63-71,73-75,97H,14,20-29,33,35-48,50,90-95H2,1-13H3,(H2,96,113)(H,98,124)(H,99,112)(H,100,116)(H,101,122)(H,102,123)(H,103,120)(H,104,125)(H,105,115)(H,106,117)(H,107,121)(H,108,126)(H,109,114)(H,110,118)(H,111,119)/t56-,57-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,73-,74-,75-/m0/s1

InChIKey

WMTUWZOBAVPERW-VZYQMWHSSA-N

LogP

0.3456000000000361

Topological Polar Surface Area

622.3999999999997 Å²

Hydrogen Bond Donor/Acceptor

29 / 37

Complexity

3380

Synonyms & References

English

157606-25-2
L-Leucinamide,L-lysyl-L-tryptophyl-L-lysyl-L-leucyl-L-phenylalanyl-L-lysyl-L-lysyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-
CHEMBL1214077
Cecropin A (1-7)-Melittin A (2-9) amide
Cecropin A (1-7)-Melittin A (2-9)
L-Leucinamide,L-lysyl-L-tryptophyl-L-lysyl-L-leucyl-L-phenylalanyl-L-lysyl-L-lysyl-L-isoleucyl...
L-Leucinamide,L-lysyl-L-tryptophyl-L-lysyl-L-leucyl-L-phenylalanyl-L-lysyl-L-lysyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucy
CECROPIN A-MELITTIN HYBRID PEPTIDE
Cecropin A-melittin hybrid peptide [CA(1-7)M(2-9)NH2]
H-LYS-TRP-LYS-LEU-PHE-LYS-LYS-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-NH2
KWKLFKKIGAVLKVL-amide
KWKLFKKIGAVLKVL-NH2
LYS-TRP-LYS-LEU-PHE-LYS-LYS-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-NH2
CA(1-7)M(2-9)NH2
CECROPIN A (1-8)-MELITTIN A (3-9) AMIDE
CAMEL0, Cecropin A (1-8)-Melittin A (3-9) aMide, CM15
Cecropin A (1-7)-Melittin A (2-9) amide , Cecropin A (1-8)-Melittin A (3-9) amide
Cecropin A (1-7)-Melittin A (2-9) aMide CAMEL0, Cecropin A (1-8)-Melittin A (3-9) aMide, CM15
Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt

MDL Number

MFCD01630779

FAQ

What are the physical and chemical properties of Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2)?

Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2) is a peptide compound known for its crystalline form. It has a molecular weight of approximately 2,315.5 g/mol and is soluble in water. The compound is known for its antimicrobial and cytotoxic properties. It is reactive towards various proteins and can form stable amide bonds under mild conditions.

How is Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2) typically synthesized?

Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2) is typically synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Commonly, the synthesis involves protecting groups, coupling reactions, and deprotection steps. The product is then purified and characterized to ensure high selectivity and yield.

What industries use Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2)?

Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2) is used in various industries, particularly in pharmaceuticals for its antimicrobial properties. It is also explored in polymer science for its potential to enhance material properties, and in biotechnology for its role in biosensors and semiconductors.

What precautions should be taken when handling Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2)?

When handling Cecropin A (1-7)-Melittin A (2-9) amide (CAS: 157606-25-2), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.