2-(2,4-Dichlorobenzyl)-1H-benzimidazole

Basic Information

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CAS Number

154660-96-5

Molecular Formula

C14H10Cl2N2

Molecular Weight

277.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC=C2C(=C1)NC(=N2)CC3=C(C=C(C=C3)Cl)Cl

InChI

InChI=1S/C14H10Cl2N2/c15-10-6-5-9(11(16)8-10)7-14-17-12-3-1-2-4-13(12)18-14/h1-6,8H,7H2,(H,17,18)

InChIKey

OIHHDYNKEHASLI-UHFFFAOYSA-N

LogP

4.460500000000002

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

287

Synonyms & References

English

2-(2,4-Dichlorobenzyl)-1H-benzo[d]imidazole
BDBM50404893
MFCD01250229
BCP13086
1H-Benzimidazole, 2-[(2,4-dichlorophenyl)methyl]-
SCHEMBL2948135
DTXSID70366569
2-[(2,4-dichlorophenyl)methyl]-1H-1,3-benzodiazole
AKOS001057329
2-(2,4-Dichloro-benzyl)-1H-benzoimidazole
2-(2,4-DICHLOROBENZYL)-1H-BENZIMIDAZOLE
CS-0155895
CHEMBL355666
AM84505
2-[(2,4-dichlorophenyl)methyl]-1H-benzimidazole
1H-Benzimidazole,2-[(2,4-dichlorophenyl)methyl]-
FT-0688155
Z55692933
2-((2,4-dichlorophenyl)methyl)-1h-benzimidazole
AC-22666
DS-18576
154660-96-5
2-[(2,4-dichlorophenyl)methyl]-1H-Benzimidazole
2-(2,4-Dichlorobenzyl)-1H-b
2-(2,4-Dichlorobenzyl)benziMidazole
2-(2,4-two chlorobenzyl)benziMidazole
2-(2,4-Dichlorobenzyl)-1H-benzimidazole
2-[(2,4-Dichlorophenyl)methyl]-1H-benzimid

MDL Number

MFCD01250229

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-(2,4-Dichlorobenzyl)-1H-benzimidazole (CAS: 154660-96-5)?

2-(2,4-Dichlorobenzyl)-1H-benzimidazole is a crystalline compound with a molecular weight of approximately 305.04 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and methanol. This compound exhibits good thermal stability but can react with reducing agents. It is not highly reactive under normal conditions but should be stored in a dry, cool place away from direct sunlight.

How is 2-(2,4-Dichlorobenzyl)-1H-benzimidazole (CAS: 154660-96-5) typically synthesized?

2-(2,4-Dichlorobenzyl)-1H-benzimidazole is commonly synthesized via the condensation of 2,4-dichlorobenzyl chlorides with 1H-benzimidazole. This reaction is typically catalyzed by a basic reagent like triethylamine and proceeds with good yield and selectivity. The process involves careful control of reaction conditions to avoid side reactions.

What industries use 2-(2,4-Dichlorobenzyl)-1H-benzimidazole (CAS: 154660-96-5)?

2-(2,4-Dichlorobenzyl)-1H-benzimidazole is primarily used in the pharmaceutical industry for its biological activity, particularly as a potential antiviral and antitumor agent. It is also explored in the sensor industry due to its unique chemical and physical properties, making it suitable for detecting specific chemical species.

What precautions should be taken when handling 2-(2,4-Dichlorobenzyl)-1H-benzimidazole (CAS: 154660-96-5)?

When handling 2-(2,4-Dichlorobenzyl)-1H-benzimidazole, ensure the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.