2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid

Basic Information

View in Editor

CAS Number

150256-42-1

Molecular Formula

C22H17NO4

Molecular Weight

359.38 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

216-218 °C

Boiling Point

537.6±33.0 °C at 760 mmHg

Density

g/cm3

Water Solubility

Soluble in water or 1% acetic acid.

Flash Point

278.9±25.4 °C

SMILES

View in Editor

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC4=CC=CC=C4C(=O)O

InChI

InChI=1S/C22H17NO4/c24-21(25)18-11-5-6-12-20(18)23-22(26)27-13-19-16-9-3-1-7-14(16)15-8-2-4-10-17(15)19/h1-12,19H,13H2,(H,23,26)(H,24,25)

InChIKey

CNAVPEPPAVHHKN-UHFFFAOYSA-N

LogP

4.745800000000004

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

528

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

150256-42-1
Fmoc-2-Abz-OH
N-Fmoc-anthranilic acid
M06085
AKOS009156751
MFCD00235883
CHEBI:183678
CHEMBL524172
2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]benzoic Acid
Fmoc-2-Abz-OH, 97%
Bio4A5
Z1136511498
FT-0679799
2-(((9H-fluoren-9-yl)methoxy)carbonylamino)benzoic acid
2-{[(9H-9-fluorenylmethoxy)carbonyl]amino}benzoic acid
Oprea1_661448
BENZOIC ACID, 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-
2-N-FMOC-AMINOBENZOIC ACID
2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]benzoic Acid
2-(Fmoc-amino)benzoic acid
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)benzoic acid
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)benzoic acid
HMS1526J08
BDBM196155
N-2-(9-FLUORENYLMETHYLOXYCARBONYL)AMINO-BENZOIC ACID
Fmoc-(2)Abz-OH
BRD-K68581587-001-01-2
SY051364
CCG-254198
A884184
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]anthranilic Acid

MDL Number

MFCD00235883

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1)?

2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1) is a crystalline white solid with a molecular weight of approximately 473.41 g/mol. It is slightly soluble in water and has good solubility in organic solvents. The compound is not particularly reactive under normal conditions but can undergo hydrolysis and other acid/base reactions. It is stable under neutral to slightly acidic conditions but should be handled with care to avoid strong bases or acids.

How is 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1) typically synthesized?

2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid is typically synthesized by reacting fluoren-9-ylmethanol with benzoic anhydride in the presence of a catalytic amount of a suitable acid, such as sulfuric acid. The reaction involves the formation of an ester followed by the introduction of an amino group. The yield is generally high, and the product can be purified by recrystallization from appropriate solvents.

What industries use 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1)?

2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1) is primarily used in the pharmaceutical industry for drug synthesis. It is also utilized in the polymer industry for the development of special polymers. Additionally, it has applications in the sensor technology and semiconductor industries, where its unique functional groups facilitate specific interactions and chemical processes.

What precautions should be taken when handling 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1)?

When handling 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid (CAS: 150256-42-1), it is important to use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a fume hood to prevent inhalation of any potentially harmful vapors. Spills should be cleaned up immediately using appropriate tools and materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.