N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (1:1) | CAS No. 149436-41-9

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (1:1)

Basic Information

CAS Number

149436-41-9

Molecular Formula

C16H19ClN2O5S

Molecular Weight

386.86 g/mol

AD

Basic Physical Properties

Boiling Point

526°C at 760 mmHg

Flash Point

271.9°C

COC1=CC(=C(C=C1C(=O)CN)OC2=CC=CC=C2)NS(=O)(=O)C.Cl

InChI

InChI=1S/C16H18N2O5S.ClH/c1-22-15-9-13(18-24(2,20)21)16(8-12(15)14(19)10-17)23-11-6-4-3-5-7-11;/h3-9,18H,10,17H2,1-2H3;1H

InChIKey

NWUBXODWWYGUHS-UHFFFAOYSA-N

LogP

2.4222000000000006

Topological Polar Surface Area

107.72 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

513

Synonyms & References

English

  • Methanesulfonamide, N-[4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl]-, hydrochloride (1:1)
  • DS-18533
  • FT-0652091
  • C72844
  • N-(4-(2-Aminoacetyl)-5-methoxy-2-phenoxyphenyl)-methanesulfonamide hydrochloride
  • N-(4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamide HCl
  • N-(4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride
  • MFCD12911398
  • SB83703
  • N-[4-(2-aminoacetyl)-5-methoxy-2-phenoxy-phenyl]methanesulfonamide hydrochloride
  • N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide--hydrogen chloride (1/1)
  • AM20090783
  • A808892
  • 149436-41-9
  • Aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride
  • N-(4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamidehydrochloride
  • C16H19ClN2O5S
  • N-(4-glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride
  • N-[4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl]methanesulfonamide;hydrochloride
  • 2-amino-1-(2-methoxy-4-methanesulfonylamino-5-phenoxyphenyl)ethanone hydrochloride
  • CS-0150601
  • DTXSID30657703
  • AKOS015888750
  • N-(4-(2-Aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride
  • 2-Amino-1-(2-methoxy-4-methanesulfonylamino-5-phenoxyphenyl)ethanone hydrochloride
  • Methanesulfonamide, N-[4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl]-, hydrochloride
  • N-[4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl]methanesulfonamide,hydrochloride
  • N-(4-(2-Aminoacetyl)
  • Iguratimod Impurity 8
  • -5-methoxy-2-phenoxyphenyl)
  • Methanesulfonamide,N-[4-(2-aminoacetyl)-5-methoxy-2-phenoxyphenyl]-,hydrochloride

MDL Number

MFCD12911398

Customs Code

2935009090

FAQ

What are the physical and chemical properties of N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (CAS: 149436-41-9)?

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is a white crystalline powder with a molecular weight of approximately 554.74 g/mol. It has good solubility in organic solvents like DMF and DMSO but is poorly soluble in water. Chemically, it is stable under normal conditions but can react with strong bases to form the corresponding anion. The compound exhibits low reactivity with most common reagents, ensuring safety in laboratory settings.

How is N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (CAS: 149436-41-9) typically synthesized?

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is typically synthesized via an acylation reaction of a phenoxyphenol with methanesulfonamide, followed by hydrochloric acid treatment to form the hydrochloride salt. This process involves the use of catalysts such as triethylamine and requires careful control of reaction temperature and time to achieve high yield and selectivity.

What industries use N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (CAS: 149436-41-9)?

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is primarily used in the pharmaceutical industry for drug synthesis and development. It also has applications in the production of sensors and semiconductors due to its specific chemical structure. The compound's stability and reactivity make it suitable for these advanced technological applications.

What precautions should be taken when handling N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (CAS: 149436-41-9)?

When handling N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE), including gloves and lab coats. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, neutralize any remaining compound and clean up using appropriate solvents. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.

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