N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (1:1)(CAS: 149436-41-9)

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is a white crystalline powder with a molecular weight of approximately 554.74 g/mol. It has good solubility in organic solvents like DMF and DMSO but is poorly soluble in water. Chemically, it is stable under normal conditions but can react with strong bases to form the corresponding anion. The compound exhibits low reactivity with most common reagents, ensuring safety in laboratory settings.

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is typically synthesized via an acylation reaction of a phenoxyphenol with methanesulfonamide, followed by hydrochloric acid treatment to form the hydrochloride salt. This process involves the use of catalysts such as triethylamine and requires careful control of reaction temperature and time to achieve high yield and selectivity.

N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is primarily used in the pharmaceutical industry for drug synthesis and development. It also has applications in the production of sensors and semiconductors due to its specific chemical structure. The compound's stability and reactivity make it suitable for these advanced technological applications.

When handling N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE), including gloves and lab coats. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, neutralize any remaining compound and clean up using appropriate solvents. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.