Compound Q&A
How is N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (CAS: 149436-41-9) typically synthesized?
Answer
N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is typically synthesized via an acylation reaction of a phenoxyphenol with methanesulfonamide, followed by hydrochloric acid treatment to form the hydrochloride salt. This process involves the use of catalysts such as triethylamine and requires careful control of reaction temperature and time to achieve high yield and selectivity.
About
CAS No
149436-41-9
English Name
N-(4-Glycyl-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride (1:1)
Molecular Formula
C16H19ClN2O5S
Molecular Weight
386.86 g/mol
SMILES
COC1=CC(=C(C=C1C(=O)CN)OC2=CC=CC=C2)NS(=O)(=O)C.Cl
InChIKey
NWUBXODWWYGUHS-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21
