Tert-butyl chlorosulfonylcarbamate | CAS No. 147000-89-3

Tert-butyl chlorosulfonylcarbamate

Basic Information

CAS Number

147000-89-3

Molecular Formula

C5H10ClNO4S

Molecular Weight

215.66 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)NS(=O)(=O)Cl

InChI

InChI=1S/C5H10ClNO4S/c1-5(2,3)11-4(8)7-12(6,9)10/h1-3H3,(H,7,8)

InChIKey

KAJZZLBZXOBEMD-UHFFFAOYSA-N

LogP

0.9946999999999999

Topological Polar Surface Area

72.47 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

260

Synonyms & References

English

  • Carbamic acid, (chlorosulfonyl)-, 1,1-dimethylethyl ester
  • 2-Methyl-2-propanyl (chlorosulfonyl)carbamate
  • N-(tert-butoxycarbonyl)sulfamoyl chloride
  • 2-amino-l-(N'-tert-butoxycarbonylamino)ethane
  • chlorosulfonyl carbamic acid tert-butyl ester
  • chlorure de N-tert-butoxycarbonyle-sulfamoyle
  • N-Boc-sulfamoyl chloride
  • N'-ethylhydrazinecarboxylic acid tert-butyl ester
  • N-ethyl-N'-Boc hydrazine
  • t-butoxycarbonylamino-ethylamine
  • t-butoxycarbonylaminosulfonyl chloride
  • tert-butoxycarbonylamino sulfonyl chloride
  • tert-butyl 2-ethylhydrazinecarboxylate
  • tert-butyl chlorosulfonylcarbaMate
  • CarbaMic acid, N-(chlorosulfonyl)-, 1,1-diMethylethyl ester
  • tert-butyl N-(chlorosulfonyl)carbamate
  • tert-butyl(chlorosulfonyl)carbamate
  • [(1,1-dimethylethoxy)carbonyl]-sulfamoyl chloride
  • tert-butyl [chlorosulfonyl]carbamate
  • N-(Chlorosulfonyl)-carbamic acid 1,1-dimethylethyl ester
  • N-tert-butoxycarbonylsulfamoyl chloride
  • N-Boc sulfamoyl chloride
  • tert-butyl chlorosulfonylcarbamate
  • Cl-SO2-NH-Boc
  • tert-butyl[chlorosulfonyl]carbamate
  • t-butyl(chlorosulfonyl)carbamate
  • EN300-118173
  • BS-52475
  • AKOS006333628
  • SY024657
  • CS-0147276

MDL Number

MFCD15475085

FAQ

What are the physical and chemical properties of Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3)?

Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3) is a white crystalline solid with a molecular weight of approximately 199.6 g/mol. It is slightly soluble in water and highly soluble in organic solvents like ethanol and acetonitrile. The compound is known for its reactivity, particularly in nucleophilic substitution reactions. It has a melting point of 118-120°C and is stable under normal storage conditions but requires careful handling due to its reactivity.

How is Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3) typically synthesized?

Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3) is typically synthesized by the reaction of tert-butyl carbamate with chlorosulfonyl isocyanate. The process involves stirring these reagents together under anhydrous conditions to achieve high yield and selectivity. The reaction is carried out in a suitable solvent such as dichloromethane, and the product is isolated by conventional methods like filtration and recrystallization.

What industries use Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3)?

Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3) is primarily used in the pharmaceutical and chemical industries for its reactivity and usefulness in organic synthesis. It serves as an important intermediate in the synthesis of various drugs and other functional materials. Its role in the polymer industry is also significant, where it is used as a cross-linking agent and in the development of new materials with enhanced properties.

What precautions should be taken when handling Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3)?

When handling Tert-Butyl chlorosulfonylcarbamate (CAS: 147000-89-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Storage should be in a cool, dry place away from direct sunlight. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.

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