2-Methyl-2-propanyl [(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenyl-2-hexanyl]carbamate | CAS No. 144163-85-9
2-Methyl-2-propanyl [(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenyl-2-hexanyl]carbamate
Basic Information
CAS Number
144163-85-9
Molecular Formula
C23H32N2O3
Molecular Weight
384.52 g/mol
AD
Basic Physical Properties
Melting Point
128-133°C
Density
1.110
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- tert-Butyl ((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate
- tert-Butyl (2S,4S,5S)-N-(4-amino-1-benzyl-3-hydroxy-5-phenylpentyl)carbamate
- tert-butyl(1s,3s,4s)-4-amino-1-benzyl-3-hydroxy-5-phenylpentylcarbamate
- C23H32N2O3
- UKFHOTNATOJBKZ-ACRUOGEOSA-N
- [2S,3S,5S]-2-Amino-3-hydroxy-5-t-butyloxycarbonylamino-1,6-diphenylhexane
- 144163-85-9
- (2S,4S,5S)-5-Amino-2-(Boc-amino)-4-hydroxy-1,6-diphenylhexane
- AKOS015896454
- CS-0130712
- (2S,3S,5S)-2-amino-5-[N-(tert-butyloxycarbonyl)amino]-1,6-diphenyl-3-hydroxy hexane
- A808183
- [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid 1,1-dimethyl ethyl ester
- SCHEMBL2059435
- UNII-0N59F56PQ6
- [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic acid 1,1-dimethylethyl ester
- DTXSID10932247
- [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]carbamic acid 1,1-dimethyl ethyl ester
- 0N59F56PQ6
- Carbamic acid,[(1s,2s,4s)-4-amino-3-Hydroxy-5-phenyl-1-phenylmethyl]pentyl-1,1-dimethylethyl ester
- tert-butyl(1S,3S,4S)-1-benzyl-3-hydroxy-5-phenyl-4-amino-pentylcarbamate
- Carbamic acid, N-[(1S,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 1,1-dimethylethyl ester
- AKOS015841346
- (2S,3S,5S)-2-AMINO-3-HYDROXY-5-(TERT-BUTYLOXYCARBONYLAMINO)-1,6-DIPHENYLHEXANE
- (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane
- tert-Butyl hydrogen (5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbonimidate
- tert-butyl N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate
- MFCD09833420
- A-88820
- [(1S,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic acid 1,1-dimethylethyl ester, AldrichCPR
- (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1.6-diphenylhexane
MDL Number
MFCD09833420
FAQ
What are the physical and chemical properties of (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate (CAS: 144163-85-9)?
The compound (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate has a crystalline form and a molecular weight of approximately 361.34 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity, particularly towards nucleophiles such as amines and hydroxides. It is stable under normal conditions but should be handled in a fume hood to avoid inhalation.
How is (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate (CAS: 144163-85-9) typically synthesized?
This compound is typically synthesized via a multi-step process involving the condensation of an amino alcohol with an acid chloride, followed by deprotection and diphenylation. Common catalysts include DCC (dicyclohexylcarbodiimide) and EDC (N,N′-carbonyldiimidazole). The yield is generally around 70-80%, and the reaction is carried out under anhydrous conditions to avoid side reactions.
What industries use (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate (CAS: 144163-85-9)?
This compound is used in the pharmaceutical industry for its potential as a precursor in drug synthesis. It also has applications in the development of sensors and semiconductors due to its unique chemical structure. Additionally, it may be used in the synthesis of certain polymers.
What precautions should be taken when handling (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate (CAS: 144163-85-9)?
When handling (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate, it is crucial to use personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat. In case of a spill, it should be cleaned up using appropriate methods and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information and guidance.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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