2-Methyl-2-propanyl [(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenyl-2-hexanyl]carbamate(CAS: 144163-85-9)

The compound (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate has a crystalline form and a molecular weight of approximately 361.34 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity, particularly towards nucleophiles such as amines and hydroxides. It is stable under normal conditions but should be handled in a fume hood to avoid inhalation.

This compound is typically synthesized via a multi-step process involving the condensation of an amino alcohol with an acid chloride, followed by deprotection and diphenylation. Common catalysts include DCC (dicyclohexylcarbodiimide) and EDC (N,N′-carbonyldiimidazole). The yield is generally around 70-80%, and the reaction is carried out under anhydrous conditions to avoid side reactions.

This compound is used in the pharmaceutical industry for its potential as a precursor in drug synthesis. It also has applications in the development of sensors and semiconductors due to its unique chemical structure. Additionally, it may be used in the synthesis of certain polymers.

When handling (2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenyl-2-hexanylcarbamate, it is crucial to use personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat. In case of a spill, it should be cleaned up using appropriate methods and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information and guidance.