1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea | CAS No. 1384424-80-9

Q: What precautions should be taken when handling 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

When handling 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a well-ventilated area and in a closed container to prevent exposure to moisture. In the event of a spill, the area should be ventilated, and the spill should be cleaned up using absorbent material. Always refer to the Material Safety Data Sheet (MSDS) for detailed handling and safety information.

1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea

Basic Information

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CAS Number

1384424-80-9

Molecular Formula

C17H13F3N4O2

Molecular Weight

362.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Solubility

DMSO: soluble15mg/mL, clear

SMILES

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COc1ccc2c(c1)nccc2NC(=O)Nc1cccc(n1)C(F)(F)F

InChI

InChI=1S/C17H13F3N4O2/c1-26-10-5-6-11-12(7-8-21-13(11)9-10)22-16(25)24-15-4-2-3-14(23-15)17(18,19)20/h2-9H,1H3,(H2,21,22,23,24,25)

InChIKey

VQPBIJGXSXEOCU-UHFFFAOYSA-N

LogP

4.3012000000000015

Topological Polar Surface Area

76.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Safety Information

View Safety Information

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-(7-methoxy-4-quinolinyl)-3-[6-(trifluoromethyl)-2-pyridinyl]ure
1-(7-Methoxy-4-quinolinyl)-3-[6-(trifluoromethyl)-2-pyridinyl]ure<wbr
A 1070722
1-(7-methoxy-1-benzofuran-3-yl)acetone
1-(7-methoxyquinolin-4-yl)-3-(6-trifluoromethyl-pyridin-2-yl)-urea
2-Propanone, 1-(7-methoxy-3-benzofuranyl)-
CTK2G3909
SureCN4138516
Zatebradine hydrochloride
1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea

MDL Number

MFCD22580422

FAQ

What are the physical and chemical properties of 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea is a crystalline compound with a molecular weight of approximately 469.4 g/mol. Its solubility in water is low, and it is more soluble in organic solvents such as dimethylformamide (DMF) and acetonitrile. The compound shows moderate reactivity towards nucleophiles and can undergo substitution reactions. It is stable under normal laboratory conditions but should be stored in a desiccator to prevent moisture absorption.

How is 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9) typically synthesized?

1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea can be synthesized by reacting 7-methoxy-4-quinoline with 6-(trifluoromethyl)-2-pyridine in the presence of a base like potassium carbonate. The reaction mixture is typically heated in an inert solvent such as N,N-dimethylformamide (DMF) at elevated temperatures. The yield is generally around 70-80%, and the product is purified via recrystallization from a suitable solvent.

What industries use 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea is used in the pharmaceutical industry as an intermediate in the synthesis of pharmaceutical compounds. It is also utilized in the polymer industry for its stability and reactivity. Additionally, this compound can be employed in the development of sensors and as a functional molecule in the field of organic electronics.

What precautions should be taken when handling 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

When handling 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a well-ventilated area and in a closed container to prevent exposure to moisture. In the event of a spill, the area should be ventilated, and the spill should be cleaned up using absorbent material. Always refer to the Material Safety Data Sheet (MSDS) for detailed handling and safety information.

Related Compounds

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Compound Q&A

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Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

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Compound Q&A

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1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea | CAS No. 1384424-80-9

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Solubility

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Safety Information

Hazard Statement

Synonyms & References

English

MDL Number

FAQ

What are the physical and chemical properties of 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

How is 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9) typically synthesized?

What industries use 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

What precautions should be taken when handling 1-(7-methoxy-4-quinolyl)-3-[6-(trifluoromethyl)-2-pyridyl]urea (CAS: 1384424-80-9)?

Related Compounds

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