2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate | CAS No. 135042-17-0
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate
Basic Information
CAS Number
135042-17-0
Molecular Formula
C11H19NO5
Molecular Weight
245.27 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
335.2℃ at 760 mmHg
Synonyms & References
English
- (2R,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
- (2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
- 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R-trans)-
- 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4S)-
- Boc-trans-D-Hyp-Ome
- N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
- 1-O-tert-butyl 2-O-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
- 1-tert-butyl 2-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
- MZMNEDXVUJLQAF-JGVFFNPUSA-N
- Boc-trans-4-D-Hyp-OMe
- SB18509
- FCH3937963
- ZB013281
- AB1006679
- Boc-trans-4-Hydroxy-D-prolin
MDL Number
MFCD09954932
FAQ
What are the physical and chemical properties of 2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate (CAS: 135042-17-0)?
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate is a crystalline compound with a molecular weight of approximately 262.34 g/mol. It has a solubility of about 0.015 g/L in water at 25°C. Chemically, it is reactive, particularly towards nucleophiles and reducing agents, and it can undergo esterification and amidation reactions. It is insoluble in most organic solvents except for alcohols and ethers.
How is 2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate (CAS: 135042-17-0) typically synthesized?
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate can be synthesized via the condensation of 2-methyl-1-(2-methyl-2-propanyl) pyrrolidine-2,3-dione with hydroxyacetic acid. The reaction typically involves the use of a catalyst such as 4-dimethylaminopyridine (DMAP) and proceeds with high selectivity, yielding up to 95% purity.
What industries use 2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate (CAS: 135042-17-0)?
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drug molecules. It is also explored in polymer technology for its potential use in the development of advanced materials. Additionally, it may find applications in the production of sensors and semiconductors due to its unique chemical properties.
What precautions should be taken when handling 2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate (CAS: 135042-17-0)?
When handling 2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood due to its potential to release volatile compounds. In case of a spill, immediately clean up using appropriate absorbents and consult the Safety Data Sheet (SDS) for specific instructions. Always ensure proper storage in a cool, dry place away from heat sources and oxidizing agents.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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