2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate(CAS: 135042-17-0)

2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate is a crystalline compound with a molecular weight of approximately 262.34 g/mol. It has a solubility of about 0.015 g/L in water at 25°C. Chemically, it is reactive, particularly towards nucleophiles and reducing agents, and it can undergo esterification and amidation reactions. It is insoluble in most organic solvents except for alcohols and ethers.

2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate can be synthesized via the condensation of 2-methyl-1-(2-methyl-2-propanyl) pyrrolidine-2,3-dione with hydroxyacetic acid. The reaction typically involves the use of a catalyst such as 4-dimethylaminopyridine (DMAP) and proceeds with high selectivity, yielding up to 95% purity.

2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drug molecules. It is also explored in polymer technology for its potential use in the development of advanced materials. Additionally, it may find applications in the production of sensors and semiconductors due to its unique chemical properties.

When handling 2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood due to its potential to release volatile compounds. In case of a spill, immediately clean up using appropriate absorbents and consult the Safety Data Sheet (SDS) for specific instructions. Always ensure proper storage in a cool, dry place away from heat sources and oxidizing agents.