DoMperidoneiMpurityE

Basic Information

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CAS Number

1346602-50-3

Molecular Formula

C32H34ClN7O3

Molecular Weight

600.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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Clc1ccc2c(c1)[nH]c(=O)n2C1CCN(CC1)CCCn1c(=O)n(c2c1cccc2)CCCn1c(=O)[nH]c2c1cccc2

InChI

InChI=1S/C32H34ClN7O3/c33-22-11-12-27-25(21-22)35-31(42)40(27)23-13-19-36(20-14-23)15-5-17-38-28-9-3-4-10-29(28)39(32(38)43)18-6-16-37-26-8-2-1-7-24(26)34-30(37)41/h1-4,7-12,21,23H,5-6,13-20H2,(H,34,41)(H,35,42)

InChIKey

RGMCTMMMTSTPET-UHFFFAOYSA-N

LogP

4.559900000000003

Topological Polar Surface Area

105.75 Å²

Hydrogen Bond Donor/Acceptor

2 / 10

Complexity

1040

Synonyms & References

English

Domperidone Impurity E
3’-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity E)
3’-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity E)
3'-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone(Domperidone Impurity E)
1-[3-[4-(5-Chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3-[3-(2-oxo-3H-benzimidazol-1-yl
3’-3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl Domperidone(Domperidone Impurity E) (>90%)
1-(3-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-3-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one

MDL Number

MFCD21363563

FAQ

What are the physical and chemical properties of DoMperidoneiMpurityE (CAS: 1346602-50-3)?

DoMperidoneiMpurityE is an organic compound characterized by a crystalline form with a molecular weight of approximately 352.42 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. Chemically, DoMperidoneiMpurityE is stable under normal conditions but may react with strong acids or bases. It is typically stored in a dry, cool place away from direct sunlight.

How is DoMperidoneiMpurityE (CAS: 1346602-50-3) typically synthesized?

DoMperidoneiMpurityE is synthesized through a multi-step process involving the protection and modification of a primary amine group. Commonly, this involves the use of a protecting group, followed by an amide formation step. The reaction typically uses a catalyst such as an acid or base, and the yield and selectivity vary depending on the specific conditions, with high purity products being obtained through recrystallization.

What industries use DoMperidoneiMpurityE (CAS: 1346602-50-3)?

DoMperidoneiMpurityE is primarily used in the pharmaceutical industry for the development of antipsychotic medications. It is also of interest in the research community for its potential applications in studies related to dopamine receptor function. Its use in other industries such as polymers and sensors is limited but ongoing research may expand its applications.

What precautions should be taken when handling DoMperidoneiMpurityE (CAS: 1346602-50-3)?

Handling DoMperidoneiMpurityE requires adherence to strict safety protocols. Always wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a fume hood to minimize exposure. In case of spills, neutralize with a suitable reagent and dispose of waste according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.