3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline | CAS No. 1332356-31-6
3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline
Basic Information
CAS Number
1332356-31-6
Molecular Formula
C17H17F3N2
Molecular Weight
306.33 g/mol
AD
Chemical Classification
Basic Physical Properties
Solubility
Insuluble (5.8E-3 g/L) (25 ºC),
Synonyms & References
English
- 3,5-Difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]aniline
- 3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]benzenamine
- 3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)aniline
- AMY19532
- BCP26137
- SB18185
FAQ
What are the physical and chemical properties of 3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline (CAS: 1332356-31-6)?
3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline (CAS: 1332356-31-6) is a crystalline solid with a molecular weight of approximately 411.33 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and dimethylformamide. Chemically, it is relatively stable but can react with strong acids and bases. It exhibits good reactivity in electrophilic aromatic substitution reactions.
How is 3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline (CAS: 1332356-31-6) typically synthesized?
3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline is typically synthesized via a multistep process involving the formation of a piperidine ring, followed by coupling with a fluoroaniline derivative. The synthesis often employs palladium catalysts and involves protecting groups to control the selectivity. High yields and purity can be achieved with careful optimization of reaction conditions.
What industries use 3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline (CAS: 1332356-31-6)?
3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline (CAS: 1332356-31-6) is primarily used in the pharmaceutical industry for the development of novel drugs. It also finds applications in the synthesis of functional materials for sensors and semiconductors, where its unique chemical properties make it suitable for specific reactions and functionalities.
What precautions should be taken when handling 3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline (CAS: 1332356-31-6)?
When handling 3,5-Difluoro-4-[4-(4-fluorophenyl)-1-piperidinyl]aniline, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or with a fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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