9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin | CAS No. 1329833-82-0
9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin
Basic Information
CAS Number
1329833-82-0
Molecular Formula
C23H31N5O4
Molecular Weight
441.53 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin
- (3S)-3-Methyl-9,10-bis(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- LEVOFLOXACIN IMPURITY 21
- (S)-3-Methyl-9,10-bis(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- DTXSID70747435
- 1329833-82-0
- 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin; 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-3-methyl-9,10-bis(4-methyl-1-piperazinyl)-7-oxo-, (3S)-
- Levofloxacin Impurity 6
- (2S)-2-methyl-6,7-bis(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
MDL Number
MFCD31562720
FAQ
What are the physical and chemical properties of 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0)?
9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0) is a crystalline solid with a molecular weight of approximately 418.43 g/mol. It has a high solubility in water and moderate solubility in organic solvents. The compound is relatively stable under normal conditions but is susceptible to degradation in basic conditions. It exhibits good reactivity towards nucleophiles and is often used in pharmaceutical applications.
How is 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0) typically synthesized?
9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin is typically synthesized via a multi-step process involving the modification of a fluoroquinolone core. The synthesis involves protecting groups, deprotection, and the introduction of a 4-methylpiperazine group. Common catalysts include palladium complexes, and the overall yield is around 70-80%. The process is selective and involves careful control of reaction conditions to ensure the desired product is formed.
What industries use 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0)?
9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0) is primarily used in the pharmaceutical industry. It is an active pharmaceutical ingredient (API) used in the development of new antibiotics. The compound may also find applications in veterinary medicine and could potentially be explored for use in other industries such as agriculture or biotechnology, although its main focus remains in pharmaceuticals.
What precautions should be taken when handling 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0)?
When handling 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin (CAS: 1329833-82-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a dry, cool place and away from strong acids and bases. In case of spills, immediately clean up the area using appropriate methods and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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