(1S)-1-Amino-4-indanecarbonitrile hydrochloride (1:1)

Basic Information

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CAS Number

1306763-57-4

Molecular Formula

C10H11ClN2

Molecular Weight

147.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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c1cc(c2c(c1)[C@H](CC2)N)C#N.Cl

InChI

InChI=1S/C10H10N2.ClH/c11-6-7-2-1-3-9-8(7)4-5-10(9)12;/h1-3,10H,4-5,12H2;1H/t10-;/m0./s1

InChIKey

NYCLSOKJNLLCHQ-PPHPATTJSA-N

LogP

1.94102

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

215

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-1-Amino-2,3-dihydro-1H-indene-4-carbonitrile hydrochloride
(S)-1-AMINO-2,3-DIHYDRO-1H-INDENE-4-CARBONITRILE HCl
(S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile-HCl
AX8209841
(1S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile hydrochloride
1H-Indene-4-carbonitrile, 1-amino-2,3-dihydro-, hydrochloride (1:1), (1S)-
(1S)-1-Amino-2,3-dihydro-1H-ind

MDL Number

MFCD16295046

FAQ

What are the physical and chemical properties of (1S)-1-Amino-4-indanecarbonitrile hydrochloride (CAS: 1306763-57-4)?

(1S)-1-Amino-4-indanecarbonitrile hydrochloride is a white crystalline solid with a molecular weight of approximately 258.24 g/mol. It has a low water solubility but is soluble in organic solvents like methanol and ethanol. Chemically, it is stable but can react under basic conditions. It is often used in pharmaceutical research and synthesis applications.

How is (1S)-1-Amino-4-indanecarbonitrile hydrochloride (CAS: 1306763-57-4) typically synthesized?

(1S)-1-Amino-4-indanecarbonitrile hydrochloride is synthesized via the reaction of 4-indanone with sodium cyanide in the presence of an acid catalyst. The process typically yields a product with high selectivity and good yield. The reaction is carried out in a solvent like acetonitrile, and the hydrochloride salt is formed by neutralizing the amine with hydrochloric acid.

What industries use (1S)-1-Amino-4-indanecarbonitrile hydrochloride (CAS: 1306763-57-4)?

(1S)-1-Amino-4-indanecarbonitrile hydrochloride is primarily used in the pharmaceutical industry for the synthesis of drugs. It is also utilized in the polymer industry for the development of functional polymers and in sensor technology for its electronic properties.

What precautions should be taken when handling (1S)-1-Amino-4-indanecarbonitrile hydrochloride (CAS: 1306763-57-4)?

When handling (1S)-1-Amino-4-indanecarbonitrile hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat to prevent skin contact and eye irritation. The substance should be handled in a fume hood to minimize inhalation risk. Spills should be cleaned up carefully using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.