(1S)-1-Amino-4-indanecarbonitrile hydrochloride (1:1)(CAS: 1306763-57-4)

(1S)-1-Amino-4-indanecarbonitrile hydrochloride is a white crystalline solid with a molecular weight of approximately 258.24 g/mol. It has a low water solubility but is soluble in organic solvents like methanol and ethanol. Chemically, it is stable but can react under basic conditions. It is often used in pharmaceutical research and synthesis applications.

(1S)-1-Amino-4-indanecarbonitrile hydrochloride is synthesized via the reaction of 4-indanone with sodium cyanide in the presence of an acid catalyst. The process typically yields a product with high selectivity and good yield. The reaction is carried out in a solvent like acetonitrile, and the hydrochloride salt is formed by neutralizing the amine with hydrochloric acid.

(1S)-1-Amino-4-indanecarbonitrile hydrochloride is primarily used in the pharmaceutical industry for the synthesis of drugs. It is also utilized in the polymer industry for the development of functional polymers and in sensor technology for its electronic properties.

When handling (1S)-1-Amino-4-indanecarbonitrile hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat to prevent skin contact and eye irritation. The substance should be handled in a fume hood to minimize inhalation risk. Spills should be cleaned up carefully using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.