6-Chloro-2,3-pyridinedicarboxylic acid

Basic Information

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CAS Number

127437-44-9

Molecular Formula

C7H4ClNO4

Molecular Weight

201.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC(=NC(=C1C(=O)O)C(=O)O)Cl

InChI

InChI=1S/C7H4ClNO4/c8-4-2-1-3(6(10)11)5(9-4)7(12)13/h1-2H,(H,10,11)(H,12,13)

InChIKey

UZSYXDLIFFSYNQ-UHFFFAOYSA-N

LogP

1.1314

Topological Polar Surface Area

87.49 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

233

Synonyms & References

English

Z1269219018
SCHEMBL7897938
D82302
CFA43744
6-chloropyridine-2,3-dicarboxylic Acid
DTXSID70464716
CS-0198357
6-chloropyridine-2,3-dicarboxylicAcid
6-chloro-pyridine-2,3-dicarboxylic acid
6-CHLORO-2,3-PYRIDINEDICARBOXYLIC ACID
MFCD13689014
FT-0744281
AS-80190
127437-44-9
EN300-128043
2,3-Pyridinedicarboxylic acid, 6-chloro-
6-Chloropyridine-2,3-dicarboxylic acid
6-Chloro-2,3-pyridinedicarboxylic acid
6‐CHLORO‐2,3‐PYRIDINEDICARBOXYLIC ACID
6-Chloro-pyridine-2,3-dicarboxylic acid
AGN-PC-008DGP
AK118709
CTK8E5377
KB-248245

MDL Number

MFCD13689014

FAQ

What are the physical and chemical properties of 6-Chloro-2,3-pyridinedicarboxylic acid (CAS: 127437-44-9)?

6-Chloro-2,3-pyridinedicarboxylic acid is a crystalline solid with a molecular weight of approximately 212.01 g/mol. It has a high solubility in water and a pKa of around 2.65 and 4.45. This compound is moderately reactive, showing basicity in its acidic form and acidity in its basic form. It can undergo esterification and amide formation under appropriate conditions.

How is 6-Chloro-2,3-pyridinedicarboxylic acid (CAS: 127437-44-9) typically synthesized?

6-Chloro-2,3-pyridinedicarboxylic acid is typically synthesized through the chlorination of 2,3-pyridinedicarboxylic acid with thionyl chloride. The chlorination process is conducted under anhydrous conditions to maximize the yield. The product is then purified through recrystallization from a suitable solvent to obtain the crystalline form.

What industries use 6-Chloro-2,3-pyridinedicarboxylic acid (CAS: 127437-44-9)?

6-Chloro-2,3-pyridinedicarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in the polymer industry for the synthesis of functionalized polymers and in the semiconductor industry for the production of photoresists. Additionally, it can be utilized in the development of sensors and as a precursor in various organic synthesis reactions.

What precautions should be taken when handling 6-Chloro-2,3-pyridinedicarboxylic acid (CAS: 127437-44-9)?

When handling 6-Chloro-2,3-pyridinedicarboxylic acid, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be used in a fume hood to minimize exposure. In case of a spill, it should be handled using appropriate spill kits. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS).