2,4,6-Trichloronicotinaldehyde

Basic Information

View in Editor

CAS Number

1261269-66-2

Molecular Formula

C6H2Cl3NO

Molecular Weight

210.45 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=C(C(=C(N=C1Cl)Cl)C=O)Cl

InChI

InChI=1S/C6H2Cl3NO/c7-4-1-5(8)10-6(9)3(4)2-11/h1-2H

InChIKey

RESMQRUOHBZJCA-UHFFFAOYSA-N

LogP

2.8543000000000003

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

155

Synonyms & References

English

EN300-134358
1261269-66-2
SCHEMBL7699406
DS-6946
J-507072
AKOS015891869
2,4,6-Trichloro-3-pyridinecarboxaldehyde, 95%
2,4,6-trichloronicotinaldehyde
MFCD17012148
DTXSID10604093
A889675
H10977
2,4,6-Trichloro-3-pyridinecarboxaldehyde
SY114645
RESMQRUOHBZJCA-UHFFFAOYSA-N
2,4,6-trichloropyridine-3-carbaldehyde
3-Pyridinecarboxaldehyde, 2,4,6-trichloro-
CS-0047127
2,4,6-Trichloronicotinaldehyde
2,4,6-Trichloronicotildehyde

MDL Number

MFCD17012148

FAQ

What are the physical and chemical properties of 2,4,6-Trichloronicotinaldehyde (CAS: 1261269-66-2)?

2,4,6-Trichloronicotinaldehyde is a white crystalline solid with a molecular weight of approximately 217.07 g/mol. It has low water solubility and is moderately soluble in organic solvents. This compound is known for its reactivity with nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from moisture and reducing agents.

How is 2,4,6-Trichloronicotinaldehyde (CAS: 1261269-66-2) typically synthesized?

2,4,6-Trichloronicotinaldehyde is typically synthesized by chlorinating nicotinaldehyde using thionyl chloride as the chlorinating agent. The reaction is conducted in a polar aprotic solvent, and the product is isolated by recrystallization. This method provides good yield and selectivity, making it a common approach for preparing this compound in the laboratory.

What industries use 2,4,6-Trichloronicotinaldehyde (CAS: 1261269-66-2)?

2,4,6-Trichloronicotinaldehyde is used in the pharmaceutical industry for the synthesis of various intermediates and drugs. It also finds applications in the polymer industry as a crosslinking agent and in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2,4,6-Trichloronicotinaldehyde (CAS: 1261269-66-2)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat should be worn when handling 2,4,6-Trichloronicotinaldehyde. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. If a spill occurs, it should be contained and handled according to the Material Safety Data Sheet (MSDS) guidelines. Storage should be in a cool, dry place, away from reducing agents and moisture. Always refer to the latest MSDS for detailed safety information.