Compound Q&A

How is 2,4,6-Trichloronicotinaldehyde (CAS: 1261269-66-2) typically synthesized?

Answer

2,4,6-Trichloronicotinaldehyde
2,4,6-Trichloronicotinaldehyde is typically synthesized by chlorinating nicotinaldehyde using thionyl chloride as the chlorinating agent. The reaction is conducted in a polar aprotic solvent, and the product is isolated by recrystallization. This method provides good yield and selectivity, making it a common approach for preparing this compound in the laboratory.

About

English Name 2,4,6-Trichloronicotinaldehyde
Molecular Formula C6H2Cl3NO
Molecular Weight 210.45 g/mol
SMILES C1=C(C(=C(N=C1Cl)Cl)C=O)Cl
InChIKey RESMQRUOHBZJCA-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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