1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile

Basic Information

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CAS Number

124276-61-5

Molecular Formula

C11H8F3N

Molecular Weight

200.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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FC(F)(F)c1ccc(cc1)C2(CC2)C#N

InChI

InChI=1S/C11H8F3N/c12-11(13,14)9-3-1-8(2-4-9)10(7-15)5-6-10/h1-4H,5-6H2

InChIKey

WGLHDYUQTLHLHA-UHFFFAOYSA-N

LogP

3.7569000000000017

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Synonyms & References

English

1-[4-(trifluoroMethyl)phenyl]cyclopropane-1- carbonitrile
1-(4-(Trifluoromethyl)phenyl)cyclopropane carbonitrile
1-[4-(Trifluoromethyl)phenyl]-cyclopropanecarbonitrile
1-[4-(trifluoroMethyl)phenyl]cyclopropane-1- carbonitrile
1-4-(trifluoromethyl)phenylcyclopropane-1-carbonitrile

MDL Number

MFCD07374413

FAQ

What are the physical and chemical properties of 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS: 124276-61-5)?

1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile is a colorless to white crystalline solid with a molecular weight of approximately 262.13 g/mol. It has low solubility in water but is soluble in common organic solvents like methanol and dichloromethane. The compound is known for its chemical stability and low reactivity under normal conditions, although it may undergo hydrolysis in the presence of moisture.

How is 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS: 124276-61-5) typically synthesized?

1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile is usually synthesized via a multistep process starting from 4-(trifluoromethyl)benzoyl chloride and cyclopropanecarbaldehyde. The synthesis involves nucleophilic addition followed by hydrolysis and nitrile formation, requiring careful control of reaction conditions to achieve high yield and selectivity.

What industries use 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS: 124276-61-5)?

1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile is utilized in various industries, particularly in pharmaceuticals for medicinal chemistry and drug synthesis due to its unique chemical structure. It also finds applications in the polymer industry for synthesizing advanced polymers and in the electronics sector for producing semiconductor materials.

What precautions should be taken when handling 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS: 124276-61-5)?

When handling 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood to minimize inhalation of vapors. Spills should be cleaned up using absorbent materials and followed by thorough washing with water. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage guidelines.