Compound Q&A
How is 1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS: 124276-61-5) typically synthesized?
Answer
![1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile](https://static.chemtradehub.com/structs/124/124276-61-5-6f62.webp "1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile")
1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile is usually synthesized via a multistep process starting from 4-(trifluoromethyl)benzoyl chloride and cyclopropanecarbaldehyde. The synthesis involves nucleophilic addition followed by hydrolysis and nitrile formation, requiring careful control of reaction conditions to achieve high yield and selectivity.
About
CAS No
124276-61-5
English Name
1-[4-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile
Molecular Formula
C11H8F3N
Molecular Weight
200.2 g/mol
SMILES
FC(F)(F)c1ccc(cc1)C2(CC2)C#N
InChIKey
WGLHDYUQTLHLHA-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
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