3,3'-Methylenebis(6-hydroxybenzoic acid)

Basic Information

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CAS Number

122-25-8

Molecular Formula

C15H12O6

Molecular Weight

288.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

235-242 ºC

Boiling Point

350.49°C (rough estimate)

Flash Point

312.3 °C

Refractive Index

1.4413 (estimate)

SMILES

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C1=CC(=C(C=C1CC2=CC(=C(C=C2)O)C(=O)O)C(=O)O)O

InChI

InChI=1S/C15H12O6/c16-12-3-1-8(6-10(12)14(18)19)5-9-2-4-13(17)11(7-9)15(20)21/h1-4,6-7,16-17H,5H2,(H,18,19)(H,20,21)

InChIKey

JWQFKVGACKJIAV-UHFFFAOYSA-N

LogP

2.085

Topological Polar Surface Area

115.06 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

360

Synonyms & References

English

Methylenebis(salicylic acid)
5,5'-Methylenedi(salicylic acid)
D5S
2KF4FVV76N
Q27254869
NSC-14778
NSC 14778
Benzoic acid, 3,3'-methylenebis(6-hydroxy-
5,5'-Methylenedisalicyclic acid
AI3-19845
5,5-Methylenebis(salicylic acid)
122-25-8
NCGC00174622-01
CHEMBL115145
3,3'-Dicarboxy-4,4'-dihydroxydiphenylmethane
ATA fraction 9, ammonium salt
HMS1537J04
3,3'-Methylenebis(6-hydroxybenzoic acid)
MgrA inhibitor, 1
5,5'-methylenebis(salicylic acid)
chemical diversity library compound 4
Q-100103
5,5'-Methylenebis(2-hydroxybenzoicacid)
SCHEMBL160646
4,4'-Dihydroxy-3,3'-dicarboxydiphenylmethane
NSC622445
CBDivE_002544
5,5'-Methylenedisalicylic acid
5,5 '-Methylenedisalicylic acid
5,5/'-Methylenedisalicylic acid
4,3'-dicarboxydiphenylmethane

MDL Number

MFCD00016506

Customs Code

2918290000

FAQ

What are the physical and chemical properties of 3,3'-Methylenebis(6-hydroxybenzoic acid) (CAS: 122-25-8)?

3,3'-Methylenebis(6-hydroxybenzoic acid) is a crystalline compound with a molecular weight of approximately 268.15 g/mol. It has a melting point of 245-248°C. The compound is slightly soluble in water and ethanol. Chemically, it is relatively stable but can react with bases to form sodium or potassium salts. It exhibits weak acidity due to its phenolic hydroxyl groups.

How is 3,3'-Methylenebis(6-hydroxybenzoic acid) (CAS: 122-25-8) typically synthesized?

3,3'-Methylenebis(6-hydroxybenzoic acid) is typically synthesized via a condensation reaction between 6-hydroxybenzoic acid and formaldehyde. The reaction is often catalyzed by acids or bases, and the yield is usually around 85-90%. The process involves heating the reactants under reflux conditions for several hours.

What industries use 3,3'-Methylenebis(6-hydroxybenzoic acid) (CAS: 122-25-8)?

3,3'-Methylenebis(6-hydroxybenzoic acid) is used in various industries. It is a key intermediate in the production of pharmaceuticals, where it serves as a building block for certain drug molecules. In the polymer industry, it can be used to modify the properties of polymers. It also finds applications in the production of sensors and semiconductors due to its optical and electronic properties.

What precautions should be taken when handling 3,3'-Methylenebis(6-hydroxybenzoic acid) (CAS: 122-25-8)?

When handling 3,3'-Methylenebis(6-hydroxybenzoic acid), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from heat sources. In case of a spill, it should be cleaned up immediately using appropriate spill response procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety information and handling guidelines.