NBQX | CAS No. 118876-58-7

NBQX

Basic Information

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CAS Number

118876-58-7

Molecular Formula

C12H8N4O6S

Molecular Weight

336.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

361°C

Solubility

Insuluble (2.6E-3 g/L) (25 ºC),

Refractive Index

1.6000 (estimate)

SMILES

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C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3

InChI

InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)

InChIKey

UQNAFPHGVPVTAL-UHFFFAOYSA-N

LogP

2.22950

Complexity

653

Safety Information

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Stability

Freezer at -20°C

Synonyms & References

English

NBQX hydrate
Biomol-NT_000220
HMS3675G09
NCGC00024559-01
6-nitro-2,3-dioxo-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide
NBQX (FG9202)
NBQX disodium salt
1,2,3,4-tetrahydro-6-nitro-2,3-dioxobenzo[f]quinoxaline-7-sulfonamide
2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline
HMS3266I19
BDBM50207594
BCP27821
6-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-benzo[f]quinoxaline-7-sulfonic acid amide
2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline
FG 9202 disodium salt hydrate
1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide hydrate
C12H8N4O6S
2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
A11933
HB0442
SR-01000597617-1
6-nitro-2,3-dioxo-1H,2H,3H,4H-benzo[f]quinoxaline-7-sulfonamide
Benzo[f]quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-
1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrate
MB01584
2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline -7-sulfonamide
1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo(f)quinoxaline-8-sulfonamide
8LZ6Q43V2S
6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
DTXSID60152256

MDL Number

MFCD11046016

FAQ

What are the physical and chemical properties of NBQX (CAS: 118876-58-7)?

NBQX is a crystalline compound with a molecular weight of approximately 255.24 g/mol. It has a melting point of about 165°C. NBQX is slightly soluble in water and ethanol. It is moderately reactive, showing some susceptibility to oxidation under air exposure. For detailed physicochemical properties, refer to the Material Safety Data Sheet (MSDS).

How is NBQX (CAS: 118876-58-7) typically synthesized?

NBQX is usually synthesized through a multi-step process involving the condensation of 2,3-dichlorobenzaldehyde and 4-chlorobenzylamine. The reaction is typically catalyzed by Lewis acids such as aluminum chloride and proceeds with good selectivity and moderate yield. Detailed synthesis procedures can be found in academic journals and patents.

What industries use NBQX (CAS: 118876-58-7)?

NBQX is primarily used in the pharmaceutical industry for its role as a selective AMPA receptor antagonist. It is also explored in sensor technology for its ability to interact with specific chemical compounds. In addition, some research applications in semiconductor development utilize NBQX. For more specific applications, refer to recent research papers and industry reports.

What precautions should be taken when handling NBQX (CAS: 118876-58-7)?

When handling NBQX, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn to protect against potential skin contact and inhalation. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and disposed of according to hazardous waste regulations. For detailed safety information, consult the Safety Data Sheet (SDS) for NBQX (CAS: 118876-58-7).