Bis(2-methyl-2-propanyl) diethylphosphoramidoite

Basic Information

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CAS Number

117924-33-1

Molecular Formula

C12H28NO2P

Molecular Weight

249.33 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Boiling Point

39-41 °C/0.3 mmHg

Water Solubility

Hydrolyzes in water. Soluble in chloroform and methanol.

Refractive Index

n20/D 1.434(lit.)

SMILES

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CCN(CC)P(OC(C)(C)C)OC(C)(C)C

InChI

InChI=1S/C12H28NO2P/c1-9-13(10-2)16(14-11(3,4)5)15-12(6,7)8/h9-10H2,1-8H3

InChIKey

KUKSUQKELVOKBH-UHFFFAOYSA-N

LogP

4.185300000000003

Topological Polar Surface Area

21.700000000000003 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

176

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Moisture Sensitive

Sensitiveness

Moisture Sensitive

Synonyms & References

English

di-tert-butyl-N,N-diethylphosphoroamidite
[bis(tert-butoxy)phosphanyl]diethylamine
A893268
F16461
di-(tert-butyl) diethylphosphoramidite
SCHEMBL51189
KUKSUQKELVOKBH-UHFFFAOYSA-N
AKOS015915624
MFCD00134307
Di-t-butyl N,N-Diethylphosphoramidite
FT-0625353
Di-tert-butyl diethylphosphoramidite stabilized with potassium carbonate
di-tert-butyl-N,N-diethylphosphoramidite
SY019461
N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine
D4252
117924-33-1
Di-t-butyl N,N-Diethylphosphoramidite (~90%)
Di-tert-butoxy(diethylamino)phosphine
Di-tert-butyl-N,N diethylphosphoramidite
Di-tert-butyl N,N-diethylphosphoramidite
DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE
di-t-butyl diethylphosphoramidite
di(tert-butyl)N,N-diethylphosphoramidite
di-tert-butyl diethylamidophosphite
Phosphoramidous acid, diethyl-, bis(1,1-dimethylethyl) ester
J-003682
Di-tert-butyl N,N-diethylphosphoramidite, technical grade, 93%
DTXSID10401241
di-tert-butyl N,N-diethylphosphor-amidite
Di-t-butyl N,N-diethylphosphoramidite

MDL Number

MFCD00134307

FAQ

What are the physical and chemical properties of Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1)?

Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1) is a colorless or white crystalline solid with a molecular weight of approximately 289.36 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is moderately stable but can react with strong oxidizing agents. Its solubility and stability make it suitable for various applications in organic synthesis and pharmaceuticals.

How is Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1) typically synthesized?

Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1) can be synthesized through a multi-step process involving the reaction of diethyl phosphoramidite with a 2-methyl-2-propanol derivative. The synthesis typically requires the use of a catalyst such as a metal complex to enhance the reaction selectivity and yield. The process is carried out under mild conditions to avoid degradation of the product.

What industries use Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1)?

Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1) is primarily used in the pharmaceutical industry for the synthesis of bioactive molecules and in the polymer industry for modifying the chemical properties of polymers. It is also utilized in the development of sensors and semiconductors due to its unique chemical reactivity and stability.

What precautions should be taken when handling Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1)?

When handling Bis(2-methyl-2-propanyl) diethylphosphoramidoite (CAS: 117924-33-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be stored in a well-ventilated area and away from ignition sources. In case of a spill, it should be handled according to the material safety data sheet (MSDS) guidelines. Handling should be conducted in a fume hood to minimize exposure to vapors.