4-(4-Piperidinyl)aniline dihydrochloride | CAS No. 1159824-20-0

4-(4-Piperidinyl)aniline dihydrochloride

Basic Information

CAS Number

1159824-20-0

Molecular Formula

C11H18Cl2N2

Molecular Weight

249.18 g/mol

AD

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

388.5°C at 760 mmHg

Flash Point

188.7°C

Nc1ccc(cc1)C1CCNCC1.Cl.Cl

InChI

InChI=1S/C11H16N2.2ClH/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10;;/h1-4,10,13H,5-8,12H2;2*1H

InChIKey

LZONAIZKILKTNK-UHFFFAOYSA-N

LogP

2.5794000000000015

Topological Polar Surface Area

38.05 Ų

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

144

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 4-(piperidin-4-yl)aniline dihydrochloride

MDL Number

MFCD03648617

Customs Code

2933399990

FAQ

What are the physical and chemical properties of 4-(4-Piperidinyl)aniline dihydrochloride (CAS: 1159824-20-0)?

4-(4-Piperidinyl)aniline dihydrochloride is a white crystalline solid with a molecular weight of approximately 355.91 g/mol. It is soluble in water and ethanol. The compound is moderately reactive and can undergo substitution reactions. It has a pKa of about 6.3.

How is 4-(4-Piperidinyl)aniline dihydrochloride (CAS: 1159824-20-0) typically synthesized?

4-(4-Piperidinyl)aniline dihydrochloride is synthesized by the reaction of 4-piperidinyl aniline with hydrochloric acid. The reaction is carried out in an aqueous medium under stirring, with a yield of around 85%. The reaction is monitored by thin-layer chromatography (TLC) and the product is isolated by recrystallization.

What industries use 4-(4-Piperidinyl)aniline dihydrochloride (CAS: 1159824-20-0)?

4-(4-Piperidinyl)aniline dihydrochloride is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the semiconductor industry for doping applications and in the sensor industry for the development of gas sensors.

What precautions should be taken when handling 4-(4-Piperidinyl)aniline dihydrochloride (CAS: 1159824-20-0)?

When handling 4-(4-Piperidinyl)aniline dihydrochloride, wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbents, and the area should be decontaminated. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...