4-(4-Piperidinyl)aniline dihydrochloride(CAS: 1159824-20-0)

4-(4-Piperidinyl)aniline dihydrochloride is a white crystalline solid with a molecular weight of approximately 355.91 g/mol. It is soluble in water and ethanol. The compound is moderately reactive and can undergo substitution reactions. It has a pKa of about 6.3.

4-(4-Piperidinyl)aniline dihydrochloride is synthesized by the reaction of 4-piperidinyl aniline with hydrochloric acid. The reaction is carried out in an aqueous medium under stirring, with a yield of around 85%. The reaction is monitored by thin-layer chromatography (TLC) and the product is isolated by recrystallization.

4-(4-Piperidinyl)aniline dihydrochloride is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the semiconductor industry for doping applications and in the sensor industry for the development of gas sensors.

When handling 4-(4-Piperidinyl)aniline dihydrochloride, wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbents, and the area should be decontaminated. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.