Monofucosyl-para-lacto-N-hexaose IV | CAS No. 115236-58-3

Monofucosyl-para-lacto-N-hexaose IV

Basic Information

CAS Number

115236-58-3

Molecular Formula

C46H78N2O35

Molecular Weight

1219.1 g/mol

AD

Basic Physical Properties

CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)CO)O)OC5C(C(C(C(O5)CO)O)O)O)NC(=O)C)O)CO)OC6C(C(OC(C6O)OC(C(CO)O)C(C(C=O)O)O)CO)O)NC(=O)C)O)O)O

InChI

InChI=1S/C46H78N2O35/c1-11-23(60)29(66)31(68)43(72-11)81-38-22(48-13(3)57)42(83-39-27(64)18(8-53)75-45(33(39)70)78-35(15(59)5-50)24(61)14(58)4-49)77-20(10-55)36(38)79-46-34(71)40(28(65)19(9-54)76-46)82-41-21(47-12(2)56)37(26(63)17(7-52)73-41)80-44-32(69)30(67)25(62)16(6-51)74-44/h4,11,14-46,50-55,58-71H,5-10H2,1-3H3,(H,47,56)(H,48,57)/t11-,14-,15+,16+,17+,18+,19+,20+,21+,22+,23+,24+,25-,26+,27-,28-,29+,30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,40-,41-,42-,43-,44-,45-,46-/m0/s1

InChIKey

AXMANVATPOJSHN-YPTQHEKPSA-N

LogP

-15.118400000000019

Topological Polar Surface Area

590.6300000000002 Ų

Hydrogen Bond Donor/Acceptor

22 / 37

Complexity

2030

Synonyms & References

English

  • Monofucosyl-para-lacto-N-hexaose IV
  • 115236-58-3
  • MONOFUCOSYL-PARA-LACTO-N-HEXAOSE IV
  • Monofucosyl-para-lacto-N-hexaose IV (MFpLNH IV)
  • Monofucosyl-para-lacto-N-hexaose IV     (MFpLNH IV)
  • Mono-Fucosyl-p-lacto-N-hexaose Ⅳ
  • 3)]-O-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1&reg
  • 3)-O-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-(1&reg
  • 3)-O-b-D-galactopyranosyl-(1&
  • 3)-O-b-D-galactopyranosyl-(1&reg
  • FUCOSYL-PARA-LACTO-N-HEXAOSE IV FROM HUM
  • fucosyl-para-lacto-N-hexaose iv from*human milk
  • Fucosyl-para-lacto-N-hexaoseIV
  • fucosyl-p-lacto-N-hexaose IV
  • mono-Fucosyl-p-lacto-N-hexaose IV
  • β-Gal-(1-3)-β-GlcNAc-(1-3)-β-Gal-(1-4)(α-Fuc-[1-3])-β-GlcNAc-(1-3)-β-Gal-(1-4)-Glc
  • BETA-GAL-[1->3]-BETA-GLCNAC-[1->3]-BETA-GAL-[1-4][ALPHA-FUC-(1->3)]-BETA-GLCNAC-[1->3]-BETA-GAL-[1->4]-GLC

FAQ

What are the physical and chemical properties of Monofucosyl-para-lacto-N-hexaose IV (CAS: 115236-58-3)?

Monofucosyl-para-lacto-N-hexaose IV is a crystalline compound with a molecular weight of approximately 526.25 g/mol. It has a low solubility in water and is reactive under certain conditions. This compound is stable under normal storage conditions but can undergo hydrolysis in the presence of acids or bases. It is not flammable and has a melting point of around 200°C.

How is Monofucosyl-para-lacto-N-hexaose IV (CAS: 115236-58-3) typically synthesized?

Monofucosyl-para-lacto-N-hexaose IV is typically synthesized through a chemical glycosylation reaction using para-lacto-N-hexaose as the substrate and fucose as the glycosyl donor. The reaction is catalyzed by an enzyme, such as glucose-1-phosphate adenylyltransferase, and exhibits high selectivity for the desired product. The overall yield of the reaction is around 70-80%.

What industries use Monofucosyl-para-lacto-N-hexaose IV (CAS: 115236-58-3)?

Monofucosyl-para-lacto-N-hexaose IV finds applications in the pharmaceutical industry, particularly in the development of glycoconjugates and glycoproteins. It is also used in the production of sensors and semiconductors due to its unique structural properties. Additionally, it can be utilized in the polymer industry for modifying the properties of polymers through glycosylation reactions.

What precautions should be taken when handling Monofucosyl-para-lacto-N-hexaose IV (CAS: 115236-58-3)?

When handling Monofucosyl-para-lacto-N-hexaose IV (CAS: 115236-58-3), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation of dust. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.

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