2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | CAS No. 1073338-90-5

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Basic Information

CAS Number

1073338-90-5

Molecular Formula

C12H19BO3

Molecular Weight

222.09 g/mol

AD

Basic Physical Properties

Cc1oc(cc1C)B1OC(C(O1)(C)C)(C)C

InChI

1S/C12H19BO3/c1-8-7-10(14-9(8)2)13-15-11(3,4)12(5,6)16-13/h7H,1-6H3

InChIKey

QRDSPWHVPCTWNF-UHFFFAOYSA-N

LogP

2.19564

Topological Polar Surface Area

31.6 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

261

Synonyms & References

English

  • 2-(4,5-DIMETHYLFURAN-2-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
  • 4,5-Dimethylfuran-2-boronic acid pinacol ester

MDL Number

MFCD12405450

FAQ

What are the physical and chemical properties of 2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5)?

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) is a solid with a crystalline form. It has a molecular weight of approximately 256.37 g/mol. This compound is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. It exhibits typical reactivity of a dioxaborolane, which includes its ability to undergo Suzuki coupling reactions efficiently.

How is 2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) typically synthesized?

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) is typically synthesized via a multistep reaction involving the condensation of 4,5-dimethyl-2-furylboronic acid with 4,4,5,5-tetramethyl-1,3,2-dioxaborolane. The reaction is usually catalyzed by palladium under mild conditions, with high selectivity and yield. Detailed procedures can be found in literature and patents.

What industries use 2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5)?

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) is primarily used in the pharmaceutical industry for the synthesis of bioactive molecules, particularly in the development of drugs targeting various diseases. It is also utilized in the polymer industry for the synthesis of functional polymers and in the semiconductor industry for the production of advanced materials.

What precautions should be taken when handling 2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5)?

When handling 2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. This compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up with caution using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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