2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS: 1073338-90-5)

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) is a solid with a crystalline form. It has a molecular weight of approximately 256.37 g/mol. This compound is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. It exhibits typical reactivity of a dioxaborolane, which includes its ability to undergo Suzuki coupling reactions efficiently.

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) is typically synthesized via a multistep reaction involving the condensation of 4,5-dimethyl-2-furylboronic acid with 4,4,5,5-tetramethyl-1,3,2-dioxaborolane. The reaction is usually catalyzed by palladium under mild conditions, with high selectivity and yield. Detailed procedures can be found in literature and patents.

2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5) is primarily used in the pharmaceutical industry for the synthesis of bioactive molecules, particularly in the development of drugs targeting various diseases. It is also utilized in the polymer industry for the synthesis of functional polymers and in the semiconductor industry for the production of advanced materials.

When handling 2-(4,5-Dimethyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1073338-90-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. This compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up with caution using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.