2-Bromo-5-nitroaniline

Basic Information

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CAS Number

10403-47-1

Molecular Formula

C6H5BrN2O2

Molecular Weight

217.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

138.0 to 142.0 deg-C

Boiling Point

334.5 °C at 760 mmHg

Flash Point

156.1 °C

Refractive Index

1.5150 (estimate)

SMILES

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C1=CC(=C(C=C1[N+](=O)[O-])N)Br

InChI

InChI=1S/C6H5BrN2O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,8H2

InChIKey

BAAUCXCLMDAZEL-UHFFFAOYSA-N

LogP

3.04390

Complexity

159

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

MFCD00051578
2-Bromo-5-nitroaniline, 97%
B3041
CHEMBL106285
F8889-2057
AKOS000267668
Benzenamine, 2-bromo-5-nitro-
EINECS 233-874-9
SY033185
InChI=1/C6H5BrN2O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,8H
AC-25109
2-Bromo-5-nitro-phenylamine
2-bromo-5-nitrophenylamine
AE-641/00135024
SCHEMBL398996
PS-5535
10403-47-1
J-800257
4-nitro-2-aminobromobenzene
A800879
DTXSID50146225
AM806832
CS-W002243
2-bromo-5-nitro-aniline
NS00023275
2-Bromo-5-nitroaniline
BB 0304172
2-bromo-5-nitrobenzenamine
BCP05873
EN300-112742
W-108828

MDL Number

MFCD00051578

Customs Code

2921420090

FAQ

What are the physical and chemical properties of 2-Bromo-5-nitroaniline (CAS: 10403-47-1)?

2-Bromo-5-nitroaniline (CAS: 10403-47-1) is a crystalline solid with a molecular weight of approximately 216.03 g/mol. It has a high solubility in organic solvents like ethanol and acetone. The compound is known for its strong reactivity, particularly with reducing agents, and exhibits moderate acidity due to the presence of the nitro group.

How is 2-Bromo-5-nitroaniline (CAS: 10403-47-1) typically synthesized?

2-Bromo-5-nitroaniline is typically synthesized via the nitration of 2-bromobenzenamine followed by bromination. Commonly used reagents include nitric acid and sulfuric acid for nitration, and bromine in the presence of a suitable solvent for bromination. The reaction yields are around 70-80%, and the process is carried out under controlled conditions to ensure high selectivity.

What industries use 2-Bromo-5-nitroaniline (CAS: 10403-47-1)?

2-Bromo-5-nitroaniline (CAS: 10403-47-1) is primarily used in the pharmaceutical and dye industries. It serves as a precursor for the synthesis of various pharmaceuticals and dyes, including some that are used in the treatment of cardiovascular diseases and for dyeing textiles.

What precautions should be taken when handling 2-Bromo-5-nitroaniline (CAS: 10403-47-1)?

When handling 2-Bromo-5-nitroaniline (CAS: 10403-47-1), it is crucial to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposed of according to local waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.