2-Bromo-5-nitroaniline(CAS: 10403-47-1)

2-Bromo-5-nitroaniline (CAS: 10403-47-1) is a crystalline solid with a molecular weight of approximately 216.03 g/mol. It has a high solubility in organic solvents like ethanol and acetone. The compound is known for its strong reactivity, particularly with reducing agents, and exhibits moderate acidity due to the presence of the nitro group.

2-Bromo-5-nitroaniline is typically synthesized via the nitration of 2-bromobenzenamine followed by bromination. Commonly used reagents include nitric acid and sulfuric acid for nitration, and bromine in the presence of a suitable solvent for bromination. The reaction yields are around 70-80%, and the process is carried out under controlled conditions to ensure high selectivity.

2-Bromo-5-nitroaniline (CAS: 10403-47-1) is primarily used in the pharmaceutical and dye industries. It serves as a precursor for the synthesis of various pharmaceuticals and dyes, including some that are used in the treatment of cardiovascular diseases and for dyeing textiles.

When handling 2-Bromo-5-nitroaniline (CAS: 10403-47-1), it is crucial to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposed of according to local waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.