2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate | CAS No. 1038916-11-8

2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate

Basic Information

CAS Number

1038916-11-8

Molecular Formula

C24H28N4O3

Molecular Weight

420.51 g/mol

AD

Basic Physical Properties

O=C(N1CCC[C@H](C1)c1ccc(cc1)n1cc2c(n1)c(ccc2)C(=O)N)OC(C)(C)C

InChI

InChI=1S/C24H28N4O3/c1-24(2,3)31-23(30)27-13-5-7-17(14-27)16-9-11-19(12-10-16)28-15-18-6-4-8-20(22(25)29)21(18)26-28/h4,6,8-12,15,17H,5,7,13-14H2,1-3H3,(H2,25,29)/t17-/m1/s1

InChIKey

CKLLYICRBHJGHU-QGZVFWFLSA-N

LogP

4.238900000000003

Topological Polar Surface Area

90.45 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

656

Synonyms & References

English

  • tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate
  • Tert-butyl (S)-3-(4-(7-((aminooxy)carbonyl)-2H -indazol-2-yl)phenyl)piperidine-1-carboxylate
  • tert-Butyl (S)-3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate
  • CKLLYICRBHJGHU-QGZVFWFLSA-N
  • (S)-tert-Butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate
  • tert-butyl(3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate

MDL Number

MFCD26383933

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate (CAS: 1038916-11-8)?

2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate is a crystalline compound with a molecular weight of approximately 507.58 g/mol. It has limited water solubility and is generally stable under normal conditions. This compound exhibits limited reactivity, but care should be taken to avoid strong reducing agents and bases to prevent decomposition.

How is 2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate (CAS: 1038916-11-8) typically synthesized?

This compound is typically synthesized through multistep organic reactions involving the coupling of a piperidine derivative with a substituted indazolyl derivative. The synthesis often utilizes catalysts such as palladium complexes and bases like potassium carbonate. The reaction yields a mixture of isomers, with the (3S) isomer being the desired product.

What industries use 2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate (CAS: 1038916-11-8)?

This compound is primarily used in the pharmaceutical industry for the development of new drugs. It also has potential applications in the polymer industry for improving the properties of various polymers. Additionally, it may be used in the production of advanced sensors and semiconductors due to its chemical structure.

What precautions should be taken when handling 2-Methyl-2-propanyl (3S)-3-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]-1-piperidinecarboxylate (CAS: 1038916-11-8)?

When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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