Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate | CAS No. 103877-51-6
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate
Basic Information
CAS Number
103877-51-6
Molecular Formula
C16H16ClNO3
Molecular Weight
305.76 g/mol
AD
Chemical Classification
Basic Physical Properties
Density
1.362±0.06 g/cm3 (20 ºC 760 Torr),
Solubility
Insuluble (2.8E-3 g/L) (25 ºC),
Synonyms & References
English
- ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate
- 3-quinoli<wbr>
- Ethyl 7-c<wbr>
- LogP
- ethyl7-chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate
- ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate
- 103877-51-6
- DB-198310
- Ethyl 7-chloro-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylate
- CID 13657418
- DTXSID601138470
- 7-chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ethyl ester
- SCHEMBL5733774
- Ethyl7-chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate
- AMY18812
- Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate
- BCP32980
MDL Number
MFCD01912282
FAQ
What are the physical and chemical properties of Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate (CAS: 103877-51-6)?
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate is a crystalline compound with a molecular weight of approximately 324.7 g/mol. It is slightly soluble in water but soluble in organic solvents like methanol and ethanol. The compound exhibits good stability under normal temperature and pressure conditions. However, it can undergo hydrolysis in the presence of moisture and acidic or basic conditions.
How is Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate (CAS: 103877-51-6) typically synthesized?
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate is synthesized via a multistep process involving cyclization and acylation reactions. Commonly, this involves the condensation of 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline with ethyl bromoacetate in the presence of a base. The reaction is typically carried out in an anhydrous organic solvent like toluene at elevated temperatures. The yield is around 75-85%.
What industries use Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate (CAS: 103877-51-6)?
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate is primarily used in the pharmaceutical industry for intermediate steps in drug synthesis. It may also find applications in the polymer industry for the development of advanced materials and in the sensor industry for creating more sensitive detection devices. Additionally, it could be used in the semiconductor industry for specific chemical processes.
What precautions should be taken when handling Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate (CAS: 103877-51-6)?
When handling Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents, and proper disposal should follow local waste regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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