Compound Q&A
How is Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate (CAS: 103877-51-6) typically synthesized?
Answer
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate is synthesized via a multistep process involving cyclization and acylation reactions. Commonly, this involves the condensation of 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline with ethyl bromoacetate in the presence of a base. The reaction is typically carried out in an anhydrous organic solvent like toluene at elevated temperatures. The yield is around 75-85%.
About
CAS No
103877-51-6
English Name
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxoquinoline-3-carboxylate
Molecular Formula
C16H16ClNO3
Molecular Weight
305.76 g/mol
SMILES
CCOC(=O)C1=CN(C2=C(C1=O)C=CC(=C2C)Cl)C3CC3
InChIKey
MUQYAFBHOLSOCY-UHFFFAOYSA-N
Last Updated: 2025-12-31 16:27
