3-Methoxybenzenesulfonyl chloride

Basic Information

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CAS Number

10130-74-2

Molecular Formula

C7H7ClO3S

Molecular Weight

206.65 g/mol

Basic Physical Properties

Boiling Point

158-159℃/20mm

Flash Point

>230 °F

Refractive Index

n20/D 1.5560(lit.)

SMILES

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COC1=CC(=CC=C1)S(=O)(=O)Cl

InChI

InChI=1S/C7H7ClO3S/c1-11-6-3-2-4-7(5-6)12(8,9)10/h2-5H,1H3

InChIKey

JHJKSEKUZNJKGO-UHFFFAOYSA-N

LogP

1.6227

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

232

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

m-methoxybenzenesulphonyl chloride
A800369
F2167-0010
BENZENESULFONYL CHLORIDE, 3-METHOXY-
3-Methoxybenzene-1-sulfonyl chloride
3-methoxy-benzenesulfonyl chloride
3-methoxybenzene sulfonyl chloride
m-Anisolesulfonyl chloride
3-Methoxybenzene-1-sulfonylchloride
10130-74-2
AM90418
3-methoxy benzenesulfonyl chloride
3-methoxyphenylsulphonyl chloride
3-methoxybenzene sulphonyl chloride
3-Methoxybenzenesulfonyl chloride, 96%
3-(methyloxy)benzenesulfonyl chloride
3-methoxyphenylsulfonyl chloride
3-Methoxybenzenesulfonyl chloride
MFCD01318155
3-Methoxy benzene sulfonyl chloride
J-512782
CK2497
SCHEMBL18152
3-methoxybenzenesulfonylchloride
EN300-66993
M-METHOXYBENZENESULFONYL CHLORIDE
AS-7033
DTXSID30372101
AKOS000805712
FT-0615986
SY001177

MDL Number

MFCD01318155

Customs Code

2909309090

FAQ

What are the physical and chemical properties of 3-Methoxybenzenesulfonyl chloride (CAS: 10130-74-2)?

3-Methoxybenzenesulfonyl chloride is a white crystalline solid with a molecular weight of approximately 228.21 g/mol. It has a low water solubility but is soluble in organic solvents. It is highly reactive, especially towards nucleophiles, and is used in various synthetic reactions.

How is 3-Methoxybenzenesulfonyl chloride (CAS: 10130-74-2) typically synthesized?

3-Methoxybenzenesulfonyl chloride is typically synthesized by sulfonylation of 3-methoxybenzene using thionyl chloride. The reaction is performed under anhydrous conditions and is exothermic, yielding a selective and efficient product with good yield.

What industries use 3-Methoxybenzenesulfonyl chloride (CAS: 10130-74-2)?

3-Methoxybenzenesulfonyl chloride is primarily used in the pharmaceutical and polymer industries for the synthesis of intermediates. It is also used in the production of sensors and semiconductors due to its reactivity and chemical stability.

What precautions should be taken when handling 3-Methoxybenzenesulfonyl chloride (CAS: 10130-74-2)?

When handling 3-Methoxybenzenesulfonyl chloride, it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area, preferably under a fume hood, to avoid exposure. Spills should be handled carefully and according to the Material Safety Data Sheet (MSDS).