2-Fluoro-5-iodophenol

Basic Information

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CAS Number

186589-89-9

Molecular Formula

C6H4FIO

Molecular Weight

238 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC(=C(C=C1I)O)F

InChI

InChI=1S/C6H4FIO/c7-5-2-1-4(8)3-6(5)9/h1-3,9H

InChIKey

JDGBFLDXIZQLLT-UHFFFAOYSA-N

LogP

2.1358999999999995

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

99.1

Synonyms & References

English

A4127
JDGBFLDXIZQLLT-UHFFFAOYSA-N
MFCD16659616
AM85640
CS-W021694
DTXSID50677241
Phenol, 2-fluoro-5-iodo-
MB14983
FT-0687028
EN300-91919
SCHEMBL1477169
2-FLUORO-5-IODOPHENOL
AKOS015891016
DS-12576
186589-89-9
2-Fluoro-5-iodophenol
AK-33857
ANW-48957
CTK8B5500
MolPort-009-199-073
PubChem18134
SureCN1477169
2-fluoro-5-iodo-phenol
AMBZ0112
FCH1328836
PC52001
AX8159859
AB0023046
W4030
ST24028009
589F899

MDL Number

MFCD16659616

FAQ

What are the physical and chemical properties of 2-Fluoro-5-iodophenol (CAS: 186589-89-9)?

2-Fluoro-5-iodophenol (CAS: 186589-89-9) is a crystalline compound with a molecular weight of approximately 257.01 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. The compound is reactive towards bases and undergoes nucleophilic substitution reactions. It is typically stored in airtight containers to prevent moisture absorption.

How is 2-Fluoro-5-iodophenol (CAS: 186589-89-9) typically synthesized?

2-Fluoro-5-iodophenol (CAS: 186589-89-9) is typically synthesized via the iodination of 2-fluorophenol using iodine in the presence of a base such as sodium hydroxide. The reaction is carried out under mild conditions to achieve high selectivity and yield. The use of a fume hood is recommended to handle the iodine vapor.

What industries use 2-Fluoro-5-iodophenol (CAS: 186589-89-9)?

2-Fluoro-5-iodophenol (CAS: 186589-89-9) is used in various industries, particularly in the pharmaceutical sector for the synthesis of certain drugs. It also finds applications in the polymer industry for the modification of materials, in the sensor industry for developing highly sensitive sensors, and in semiconductor manufacturing for etching processes.

What precautions should be taken when handling 2-Fluoro-5-iodophenol (CAS: 186589-89-9)?

When handling 2-Fluoro-5-iodophenol (CAS: 186589-89-9), proper personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of iodine vapor. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always consult the Material Safety Data Sheet (MSDS) for detailed handling and safety information.