pyridazin-3-ylmethanol

Basic Information

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CAS Number

37444-46-5

Molecular Formula

C5H6N2O

Molecular Weight

110.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

325.7°C at 760 mmHg

SMILES

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C1=CC(=NN=C1)CO

InChI

InChI=1S/C5H6N2O/c8-4-5-2-1-3-6-7-5/h1-3,8H,4H2

InChIKey

STIKETVNLGXQCS-UHFFFAOYSA-N

LogP

-0.031100000000000128

Topological Polar Surface Area

46.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

67.4

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

PS-5744
SY013184
3-hydroxymethylpyridazine, AldrichCPR
AKOS006343254
pyridazine-3-methanol
DTXSID20383226
A823655
3-Pyridazinemethanol
3-Hydroxymethylpyridazine
SCHEMBL240861
37444-46-5
3-PYRIDAZINYLMETHANOL
3-Pyridazinmethanol
EN300-177939
(pyridazin-3-yl)methanol
AM20090601
pyridazin-3-ylmethanol
3-(Hydroxymethyl)pyridazine
PB30818
J-502088
pyridazin-3-yl-methanol
MFCD04972629
FT-0684702
STIKETVNLGXQCS-UHFFFAOYSA-N
CS-W005032
Pyridazin-3-ylmethanol
(Pyridazin-3-yl)methanol
3-HYDROXYMETHYLPYRIDAZINE
Pyridazin-3-yl-methanol
pyridazin-3-ylmethan-1-ol
SBB054829

MDL Number

MFCD04972629

Customs Code

2933990090

FAQ

What are the physical and chemical properties of pyridazin-3-ylmethanol (CAS: 37444-46-5)?

Pyridazin-3-ylmethanol (CAS: 37444-46-5) is a white crystalline solid with a molecular weight of approximately 135.13 g/mol. It is slightly soluble in water and has good solubility in common organic solvents like ethanol and acetone. Chemically, it exhibits basic properties due to the presence of the amino group and is reactive towards nucleophiles and electrophiles.

How is pyridazin-3-ylmethanol (CAS: 37444-46-5) typically synthesized?

Pyridazin-3-ylmethanol (CAS: 37444-46-5) is typically synthesized via the reduction of pyridazin-3-one with a suitable reducing agent like sodium borohydride. The reaction is carried out in an aqueous or organic solvent at room temperature, providing good yields and high selectivity.

What industries use pyridazin-3-ylmethanol (CAS: 37444-46-5)?

Pyridazin-3-ylmethanol (CAS: 37444-46-5) finds applications in the pharmaceutical industry, particularly in the synthesis of certain drug molecules. It is also used in the polymer industry as a monomer for the development of novel materials and in the electronics industry for the production of semiconductors and sensors.

What precautions should be taken when handling pyridazin-3-ylmethanol (CAS: 37444-46-5)?

When handling pyridazin-3-ylmethanol (CAS: 37444-46-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up immediately with appropriate absorbent materials and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.