Ethyl 3-amino-5-chloro-2-pyridinecarboxylate(CAS: 27330-35-4)

Ethyl 3-amino-5-chloro-2-pyridinecarboxylate (CAS: 27330-35-4) is a crystalline compound with a molecular weight of approximately 235.67 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound is moderately reactive, particularly with bases and nucleophiles. It forms colorless crystals and is stable under normal conditions.

Ethyl 3-amino-5-chloro-2-pyridinecarboxylate is typically synthesized via the reaction of 5-chloro-2-pyridinecarboxylic acid with ethylamine in the presence of a base like triethylamine. The reaction yields the desired amino compound with good selectivity and high yield. This method is commonly used in the synthesis of pharmaceutical intermediates.

Ethyl 3-amino-5-chloro-2-pyridinecarboxylate (CAS: 27330-35-4) is primarily used in the pharmaceutical and chemical industries as an intermediate for the synthesis of drugs and other organic compounds. It is also utilized in polymer chemistry for the development of advanced materials.

When handling Ethyl 3-amino-5-chloro-2-pyridinecarboxylate (CAS: 27330-35-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Use a fume hood to minimize exposure to vapors. Spills should be carefully cleaned up using absorbent materials, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.