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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide | CAS No. 879085-55-9

2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide

Basic Information

Chemical_Structure_Of
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CAS Number

879085-55-9

Molecular Formula

C19H14Cl2N2O3S

Molecular Weight

421.31 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Agricultural Chemicals Pesticides Herbicides
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

561.6°C at 760 mmHg

Density

1.440

SMILES

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O=C(c1ccc(cc1Cl)S(=O)(=O)C)Nc1ccc(c(c1)c1ccccn1)Cl

InChI

InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)

InChIKey

BPQMGSKTAYIVFO-UHFFFAOYSA-N

LogP

4.711200000000003

Topological Polar Surface Area

76.13 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
  • 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)-phenyl)-4-(methylsulfonyl)benzamide
  • 2-chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)Benzamide
  • GDC 0449
  • GDC-0449
  • GDC-0449 (Vismodegib)
  • Vismodegib
  • Vismodegib (GDC-0449)
  • Vismodegib (GDC-0449,HhAntag691, RG-3616,Erivedge®)
  • Vismodegib(GDC0449)
  • Vismodegib-D4
  • Vismodegib(GDC-0449)
  • 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (ACI)
  • Erivedge
  • 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide

MDL Number

MFCD12407408

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9)?
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9) falls under several regulatory guidelines. It is classified as a hazardous substance under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) and must comply with the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulations for EU products. In the USA, it must adhere to the regulations set by the Environmental Protection Agency (EPA) and the FDA for pharmaceuticals or industrial uses.

Are there alternatives to 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9) in synthesis?
In the synthesis of 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9), several alternatives can be used. Common substitutes include similar compounds with different functional groups, such as 2-chloro-N-phenyl-4-(methylsulfonyl)benzamide and 4-chloro-N-[3-(2-pyridinyl)phenyl]-2-(methylsulfonyl)benzamide. These alternatives can be used depending on the specific requirements of the reaction and the desired product.

What is the market or research trend for 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9)?
The market for 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9) is growing as it shows promise in various applications. Research trends indicate increasing interest in its use as a potential therapeutic agent for certain diseases. Additionally, there is a rising focus on developing more sustainable and environmentally friendly synthetic routes for this compound, driven by market demand and regulatory pressures.

How should waste containing 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9) be handled?
Waste containing 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide (CAS: 879085-55-9) should be collected in a sealed container and disposed of through a professional hazardous waste disposal service. Incineration is a common method, but strict environmental protection measures must be followed. It’s essential to comply with local regulations and ensure the waste is handled safely to prevent environmental contamination and potential health hazards.

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Supplier Information

2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide — Shanghai Yinxin Laboratory Equipment Co., Ltd.

Shanghai Yinxin Laboratory Equipment Co., Ltd.

CAS Number: 879085-55-9

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HuBeiChangXinCheng Chemical Co Ltd

CAS Number: 879085-55-9

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JiNaHuiWangYuan Chemical Co Ltd

CAS Number: 879085-55-9

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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide — ShangHaiYongCanHuaGong

ShangHaiYongCanHuaGong

CAS Number: 879085-55-9

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Wuhan HengHeDa Pharm Co., Ltd.

CAS Number: 879085-55-9

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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide — Nanjing BaiXinDeNo Bio-tech Co., Ltd

Nanjing BaiXinDeNo Bio-tech Co., Ltd

CAS Number: 879085-55-9

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Wuhan Tianzhi Biotechnology Co., Ltd.

CAS Number: 879085-55-9

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Angel Pharmatech, Ltd.

CAS Number: 879085-55-9

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Nantong Zhonghe Chemical New Materials Co., Ltd.

CAS Number: 879085-55-9

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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide — Xian Yuhui Biotechnology Co., Ltd.

Xian Yuhui Biotechnology Co., Ltd.

CAS Number: 879085-55-9

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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide — Jin Jinle (Hunan) Chemical Co., Ltd.

Jin Jinle (Hunan) Chemical Co., Ltd.

CAS Number: 879085-55-9

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Shanghai Biochempartner Co., Ltd.

CAS Number: 879085-55-9

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ShangHaiMaiKeLinShengHuaKeJi Inc

CAS Number: 879085-55-9

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Lanzhou Huahao Biopharmaceutical Technology Co., Ltd.

CAS Number: 879085-55-9

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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide — HePeng （ ShangHai ） Biotechnology Co Ltd

HePeng （ ShangHai ） Biotechnology Co Ltd

CAS Number: 879085-55-9

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