3-nitropyridin-2-amine(CAS: 4214-75-9)

3-nitropyridin-2-amine (CAS: 4214-75-9) is a crystalline compound with a molecular weight of approximately 155.08 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetonitrile. The compound is known for its stability but can react with strong acids and bases. It has a pKa of around 5.7, indicating moderate basicity.

3-nitropyridin-2-amine can be synthesized via a multi-step process. Common methods include the reduction of 3-nitropyridine with a suitable reducing agent such as sodium borohydride. The overall reaction involves the formation of the amine from the nitro group, and the process typically achieves a yield of around 70-80%. Catalysts such as palladium on carbon can be used to improve the efficiency of the reduction.

3-nitropyridin-2-amine (CAS: 4214-75-9) finds applications in various industries. It is used in pharmaceuticals for the synthesis of certain drugs, particularly in the development of anticancer and anti-inflammatory agents. It is also used in the polymer industry for the modification of polymers to improve their properties. Additionally, it has applications in the sensor and semiconductor industries due to its reactive functional groups.

When handling 3-nitropyridin-2-amine (CAS: 4214-75-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from sources of heat and ignition. It should be used in a fume hood to minimize exposure. In case of spillage, it should be cleaned up using absorbent materials and disposed of in accordance with local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.