Ethyl 5-(chloromethyl)-2-furoate(CAS: 2528-00-9)

Ethyl 5-(chloromethyl)-2-furoate (CAS: 2528-00-9) is a crystalline compound with a molecular weight of approximately 186.04 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, particularly with nucleophiles and bases. It is stable under normal conditions but should be stored in a dry, cool place away from direct sunlight.

Ethyl 5-(chloromethyl)-2-furoate (CAS: 2528-00-9) can be synthesized via the reaction of ethyl furan-2-carboxylate with phosgene in the presence of a catalyst such as N,N-dimethylformamide (DMF). The reaction produces the title compound with good yield and selectivity. This method is commonly used in academic and industrial settings.

Ethyl 5-(chloromethyl)-2-furoate (CAS: 2528-00-9) is primarily used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also utilized in the chemical industry for the production of intermediates and in the sensor technology sector for developing gas sensors. Its unique properties make it valuable in these and other specialized applications.

When handling Ethyl 5-(chloromethyl)-2-furoate (CAS: 2528-00-9), ensure proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and used under a fume hood to minimize inhalation risk. In case of spills, neutralize with an appropriate base and clean up with absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.