1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone

Basic Information

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CAS Number

106516-24-9

Molecular Formula

C24H26ClFN4O

Molecular Weight

440.95 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

155°C

Boiling Point

592.1°Cat760mmHg

Flash Point

311.9°C

Solubility

DMSO: >10mg/mL

Refractive Index

1.67

SMILES

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C1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O

InChI

InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)

InChIKey

GZKLJWGUPQBVJQ-UHFFFAOYSA-N

LogP

4.627600000000004

Topological Polar Surface Area

40.51 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

623

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

CAS-106516-24-9
1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone
CHEMBL12713
1-(2-(4-(5-Chloro-1-(p-fluorophenyl)indol-3-yl)piperidino)ethyl)-2-imidazolidinone
SR-01000872708
HY-14543
HMS3713P22
2-Imidazolidinone, 1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-
SERTINDOLE [USAN]
C07567
EN300-19767761
NCGC00181782-02
1-[2-[4-[5-chloro-1-(4-fluorophenyl)-1h-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone
SERTINDOLE [INN]
AKOS015962616
DTXCID3028893
1-[2-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
PS35 - Sertindole
EX-A883
SMR002204118
Q418050
AS-56243
D00561
5-Chloro-1-(4'-fluorophenyl)-3-(1-(2-imidazolidinon-1-ylethyl)-4-piperidyl)-1H-indole
Lu-23-174
106516-24-9
S0942
Tox21_113421
CCG-220640
NS00005623
NCGC00181782-03

MDL Number

MFCD00867749

FAQ

What regulatory guidelines apply to 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9)?

The compound 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9) is subject to various regulatory guidelines. In the European Union, it falls under the scope of the REACH regulation and must comply with the requirements for registration and safety data sheets. In the United States, it is also regulated by the EPA under the Toxic Substances Control Act (TSCA) and may require specific handling and reporting under the FDA guidelines for pharmaceuticals.

Are there alternatives to 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9) in synthesis?

Alternatives to 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9) in synthesis include its analogs with different substituents, such as changing the fluorophenyl group to a chlorophenyl group. Common alternative reagents might include other indole derivatives or piperidine analogs. These alternatives can offer different chemical properties and synthetic pathways.

What is the market or research trend for 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9)?

The market trend for 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9) is closely linked to the development of new drug candidates in oncology and neurology. Research in this compound is focusing on its potential as an antineoplastic agent. Market dynamics suggest an increasing interest in novel indole-based compounds for therapeutic applications, indicating a growing trend in drug discovery and development.

How should waste containing 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9) be handled?

Waste containing 1-(2-{4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl}ethyl)-2-imidazolidinone (CAS: 106516-24-9) should be managed according to the waste segregation and disposal regulations. Collection of waste should be done in leak-proof containers and stored separately. For incineration, it is recommended to follow approved protocols for hazardous waste. Professional waste disposal services should be used for final disposal to ensure compliance with environmental protection regulations.