2-chloro-3-methyl-5-nitropyridine

Basic Information

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CAS Number

22280-56-4

Molecular Formula

C6H5ClN2O2

Molecular Weight

172.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

47.0 to 51.0 deg-C

Boiling Point

145°C/18mmHg

Refractive Index

1.5500 (estimate)

SMILES

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CC1=CC(=CN=C1Cl)[N+](=O)[O-]

InChI

InChI=1S/C6H5ClN2O2/c1-4-2-5(9(10)11)3-8-6(4)7/h2-3H,1H3

InChIKey

OSIOIGXJUZTWRI-UHFFFAOYSA-N

LogP

2.47480

Complexity

159

Safety Information

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GHS Hazard Pictograms

H301

H315

H318

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Hygroscopic

Synonyms & References

English

2-Chloro-5-nitro-3-picoline
UNII-45ZN7UCB3M
EN300-63950
BCP22226
HY-32796
SB20915
W-206744
NSC63887
EINECS 244-889-5
InChI=1/C6H5ClN2O2/c1-4-2-5(9(10)11)3-8-6(4)7/h2-3H,1H3
2-Chloro-5-nitro-3-picoline (2-Chloro-3-methyl-5-nitropyridine)
A4785
2-Chloro-3-methyl-5nitropyridine
NS00027118
2-Chloro-3-methyl-5-nitropyridine
AM20050960
NSC 63887
PB25986
AKOS005064142
2-chloro-3-methyl-5-nitro-pyridine
Z991524294
PS-4180
MFCD00173686
SY004411
45ZN7UCB3M
Pyridine, 2-chloro-3-methyl-5-nitro-
2-chloro-5-nitro-3-methylpyridine
22280-56-4
NSC-63887
OSIOIGXJUZTWRI-UHFFFAOYSA-N
2-Chloro-3-methyl-5-nitropyridine, 97%

MDL Number

MFCD00173686

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4)?

2-Chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the European Union, and FDA/EPA guidelines in the United States. It is classified as a hazardous substance due to its potential health and environmental impacts, requiring appropriate safety data sheets and handling procedures.

Are there alternatives to 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4) in synthesis?

Alternatives to 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4) include other pyridine derivatives such as 3-chloro-2-methyl-5-nitropyridine or 2-nitro-3-methylpyridine. These can serve as viable substitutes in certain synthetic pathways, depending on the specific reaction conditions and desired end-products.

What is the market or research trend for 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4)?

The market for 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4) is driven by its use in pharmaceuticals and agrochemicals. Research trends indicate an increasing focus on developing more environmentally friendly alternatives, as well as exploring its applications in new chemical synthesis methods and medicinal chemistry.

How should waste containing 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4) be handled?

Waste containing 2-chloro-3-methyl-5-nitropyridine (CAS: 22280-56-4) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method, provided it is done in an environmentally compliant manner. Proper environmental protection measures, including the use of personal protective equipment and adherence to local regulations, are essential to prevent contamination and ensure safety.